25 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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187PubMed Papers
21Diseases
0Drugs
7Pathogenic Variants
FUNCTIONAL ROLEHub GeneReceptor
CLINICALOMIM Disease Gene
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
endoplasmic reticulumendoplasmic reticulum membranemembraneperinuclear region of cytoplasmspastic paraplegia 89, autosomal recessivebreast carcinomabreast cancerUterine leiomyoma
AI summary not yet available. Showing NCBI Gene summary.
autocrine motility factor receptor
⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
spastic paraplegia 89, autosomal recessiveOpen Targets
breast carcinomaOpen Targets
breast cancerOpen Targets
Uterine leiomyomaOpen Targets
neurodegenerative diseaseOpen Targets
optic neuritisOpen Targets
marfanoid habitus and intellectual disabilityOpen Targets
Primary amenorrheaOpen Targets
breast ductal adenocarcinomaOpen Targets
Alzheimer diseaseOpen Targets
Ehlers-Danlos syndrome, musculocontractural typeOpen Targets
papillary thyroid carcinomaOpen Targets
thyroid cancerOpen Targets
in situ carcinomaOpen Targets
non-alcoholic steatohepatitisOpen Targets
hepatocellular carcinomaOpen Targets
Spastic paraplegia 89, autosomal recessiveUniProt
NM_001144.6(AMFR):c.707+1G>ALikely pathogenic
Spastic paraplegia 89, autosomal recessive|Nonpapillary renal cell carcinoma|Thyroid cancer, nonmedullary, 1
★☆☆☆2024
NM_001144.6(AMFR):c.1092T>A (p.Cys364Ter)Pathogenic
not provided
★☆☆☆2023→ Residue 364
NM_001144.6(AMFR):c.254G>A (p.Trp85Ter)Pathogenic
Spastic paraplegia 89, autosomal recessive
☆☆☆☆2023→ Residue 85
NM_001144.6(AMFR):c.871_874dup (p.Leu292fs)Pathogenic
Spastic paraplegia 89, autosomal recessive
☆☆☆☆2023→ Residue 292
NM_001144.6(AMFR):c.1086-97_1380+375delPathogenic
Spastic paraplegia 89, autosomal recessive
☆☆☆☆2023
NM_001144.6(AMFR):c.369G>A (p.Trp123Ter)Pathogenic
Spastic paraplegia 89, autosomal recessive
☆☆☆☆2023→ Residue 123
NM_001144.6(AMFR):c.12del (p.Phe5fs)Pathogenic
Spastic paraplegia 89, autosomal recessive
☆☆☆☆2023→ Residue 5