Showing 1–50 of 20,598 genes
| # | Gene | Name | Chr | Tags | PubMed | PubMed Papers |
|---|---|---|---|---|---|---|
| 1 | TP53 | tumor protein p53 | 17 | Hub GeneTranscription Factor | 11,616 | 11,616 |
| 2 | EGFR | epidermal growth factor receptor | 7 | Hub GeneKinase | 6,679 | 6,679 |
| 3 | TNF | tumor necrosis factor | 6 | Hub GeneOMIM Disease Gene | 6,446 | 6,446 |
| 4 | IL6 | interleukin 6 | 7 | Hub GeneFDA Approved Target | 5,468 | 5,468 |
| 5 | APOE | apolipoprotein E | 19 | Hub GeneTransporter | 5,224 | 5,224 |
| 6 | VEGFA | vascular endothelial growth factor A | 6 | FDA Approved TargetOMIM Disease Gene | 5,212 | 5,212 |
| 7 | TGFB1 | transforming growth factor beta 1 | 19 | Hub GeneFDA Approved Target | 5,005 | 5,005 |
| 8 | HIF1A | hypoxia inducible factor 1 subunit alpha | 14 | Hub GeneTranscription Factor | 3,910 | 3,910 |
| 9 | MTHFR | methylenetetrahydrofolate reductase | 1 | OMIM Disease GeneHighly Studied | 3,862 | 3,862 |
| 10 | AKT1 | AKT serine/threonine kinase 1 | 14 | Hub GeneKinase | 3,746 | 3,746 |
| 11 | STAT3 | signal transducer and activator of transcription 3 | 17 | Highly ConstrainedHub Gene | 3,704 | 3,704 |
| 12 | ESR1 | estrogen receptor 1 | 6 | Hub GeneReceptor | 3,639 | 3,639 |
| 13 | IL10 | interleukin 10 | 1 | Hub GeneHighly Studied | 3,486 | 3,486 |
| 14 | BRCA1 | BRCA1 DNA repair associated | 17 | DNA RepairHomologous Recombination | 3,447 | 3,447 |
| 15 | NFKB1 | nuclear factor kappa B subunit 1 | 4 | Highly ConstrainedHub Gene | 3,393 | 3,393 |
| 16 | CTNNB1 | catenin beta 1 | 3 | Highly ConstrainedHub Gene | 3,365 | 3,365 |
| 17 | ERBB2 | erb-b2 receptor tyrosine kinase 2 | 17 | Hub GeneKinase | 3,351 | 3,351 |
| 18 | IL1B | interleukin 1 beta | 2 | Hub GeneFDA Approved Target | 3,215 | 3,215 |
| 19 | APP | amyloid beta precursor protein | 21 | Hub GeneFDA Approved Target | 3,196 | 3,196 |
| 20 | MMP9 | matrix metallopeptidase 9 | 20 | Hub GeneProtease | 3,163 | 3,163 |
| 21 | KRAS | KRAS proto-oncogene, GTPase | 12 | Highly ConstrainedHub Gene | 3,054 | 3,054 |
| 22 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 6 | Hub GeneOMIM Disease Gene | 2,871 | 2,871 |
| 23 | PTEN | phosphatase and tensin homolog | 10 | Hub GeneTumor Suppressor | 2,819 | 2,819 |
| 24 | TLR4 | toll like receptor 4 | 9 | Hub GeneReceptor | 2,775 | 2,775 |
| 25 | ACE | angiotensin I converting enzyme | 17 | Hub GeneProtease | 2,770 | 2,770 |
| 26 | BRAF | B-Raf proto-oncogene, serine/threonine kinase | 7 | Highly ConstrainedHub Gene | 2,750 | 2,750 |
| 27 | AR | androgen receptor | X | Highly ConstrainedHub Gene | 2,709 | 2,709 |
| 28 | MYC | MYC proto-oncogene, bHLH transcription factor | 8 | Highly ConstrainedHub Gene | 2,701 | 2,701 |
| 29 | CDKN2A | cyclin dependent kinase inhibitor 2A | 9 | Hub GeneTranscription Factor | 2,698 | 2,698 |
| 30 | CD274 | CD274 molecule | 9 | Hub GeneReceptor | 2,646 | 2,646 |
| 31 | ABCB1 | ATP binding cassette subfamily B member 1 | 7 | TransporterClinical Trials | 2,568 | 2,568 |
| 32 | MTOR | mechanistic target of rapamycin kinase | 1 | Highly ConstrainedHub Gene | 2,567 | 2,567 |
| 33 | BDNF | brain derived neurotrophic factor | 11 | Highly ConstrainedHub Gene | 2,558 | 2,558 |
| 34 | CXCL8 | C-X-C motif chemokine ligand 8 | 4 | Hub GeneClinical Trials | 2,501 | 2,501 |
| 35 | VDR | vitamin D receptor | 12 | ReceptorTranscription Factor | 2,491 | 2,491 |
| 36 | ADIPOQ | adiponectin, C1Q and collagen domain containing | 3 | Hub GeneOMIM Disease Gene | 2,463 | 2,463 |
| 37 | CRP | C-reactive protein | 1 | Hub GeneHighly Studied | 2,459 | 2,459 |
| 38 | SLC6A4 | solute carrier family 6 member 4 | 17 | TransporterFDA Approved Target | 2,401 | 2,401 |
| 39 | MAPK1 | mitogen-activated protein kinase 1 | 22 | Hub GeneKinase | 2,336 | 2,336 |
| 40 | PTGS2 | prostaglandin-endoperoxide synthase 2 | 1 | Highly ConstrainedHub Gene | 2,315 | 2,315 |
| 41 | PPARG | peroxisome proliferator activated receptor gamma | 3 | Hub GeneReceptor | 2,275 | 2,275 |
| 42 | GSTM1 | glutathione S-transferase mu 1 | 1 | Hub GeneHighly Studied | 2,269 | 2,269 |
| 43 | SNCA | synuclein alpha | 4 | Hub GeneClinical Trials | 2,255 | 2,255 |
| 44 | CDH1 | cadherin 1 | 16 | Hub GeneOMIM Disease Gene | 2,233 | 2,233 |
| 45 | BCL2 | BCL2 apoptosis regulator | 18 | ApoptosisHub Gene | 2,225 | 2,225 |
| 46 | HLA-B | major histocompatibility complex, class I, B | 6 | Hub GeneOMIM Disease Gene | 2,221 | 2,221 |
| 47 | MAPT | microtubule associated protein tau | 17 | Hub GeneOMIM Disease Gene | 2,219 | 2,219 |
| 48 | MDM2 | MDM2 proto-oncogene | 12 | ApoptosisHighly Constrained | 2,215 | 2,215 |
| 49 | BRCA2 | BRCA2 DNA repair associated | 13 | DNA RepairHomologous Recombination | 2,208 | 2,208 |
| 50 | NOS3 | nitric oxide synthase 3 | 7 | Hub GeneClinical Trials | 2,192 | 2,192 |