Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

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9511,000 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
951POMCproopiomelanocortin2OMIM Disease GeneHighly Studied
339
952CCT4chaperonin containing TCP1 subunit 42Highly StudiedExperimental GO Evidence
338
953CXCR3C-X-C motif chemokine receptor 3XReceptorHighly Studied
338
954IGF2Rinsulin like growth factor 2 receptor6ReceptorTransporter
338
955OLR1oxidized low density lipoprotein receptor 112ReceptorHighly Studied
338
956PSMC2proteasome 26S subunit, ATPase 27Highly ConstrainedFDA Approved Target
338
957YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta22Highly StudiedTrending
338
958ALOX5arachidonate 5-lipoxygenase10FDA Approved TargetHighly Studied
337
959L1CAML1 cell adhesion moleculeXHighly ConstrainedOMIM Disease Gene
337
960PECAM1platelet and endothelial cell adhesion molecule 117Highly StudiedExperimental GO Evidence
337
961PLA2G7phospholipase A2 group VII6Clinical TrialsOMIM Disease Gene
337
962ANGPT1angiopoietin 18Clinical TrialsOMIM Disease Gene
336
963CBX3chromobox 37Highly StudiedTrending
336
964PTK2Bprotein tyrosine kinase 2 beta8KinaseClinical Trials
336
965CD81CD81 molecule11ReceptorOMIM Disease Gene
335
966IL1R1interleukin 1 receptor type 12ReceptorFDA Approved Target
335
967NKX2-1NK2 homeobox 114Transcription FactorOMIM Disease Gene
335
968SETSET nuclear proto-oncogene9Highly ConstrainedOncogene
335
969SFNstratifin1Highly StudiedExperimental GO Evidence
335
970PGK1phosphoglycerate kinase 1XHighly ConstrainedKinase
334
971RPS19ribosomal protein S1919Highly ConstrainedFDA Approved Target
334
972SDHBsuccinate dehydrogenase complex iron sulfur subunit B1TransporterOMIM Disease Gene
334
973TSLPthymic stromal lymphopoietin5FDA Approved TargetHighly Studied
334
974AVParginine vasopressin20OMIM Disease GeneHighly Studied
333
975CCN1cellular communication network factor 11Highly StudiedExperimental GO Evidence
333
976HADHAhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha2OMIM Disease GeneHighly Studied
333
977RPL7Aribosomal protein L7a9Highly ConstrainedFDA Approved Target
333
978APLNapelinXExperimental GO EvidenceSwiss-Prot Reviewed
332
979ATXN3ataxin 314ProteaseOMIM Disease Gene
332
980LIPClipase C, hepatic type15OMIM Disease GeneExperimental GO Evidence
332
981RPS8ribosomal protein S81Highly ConstrainedFDA Approved Target
332
982SOSTsclerostin17FDA Approved TargetOMIM Disease Gene
332
983CCT6Achaperonin containing TCP1 subunit 6A7Highly ConstrainedTrending
331
984MAP3K5mitogen-activated protein kinase kinase kinase 56KinaseClinical Trials
331
985RPL6ribosomal protein L612Highly ConstrainedFDA Approved Target
331
986RPS4Xribosomal protein S4 X-linkedXFDA Approved TargetExperimental GO Evidence
331
987SLC26A4solute carrier family 26 member 47TransporterOMIM Disease Gene
331
988TMPOthymopoietin12Experimental GO EvidenceSwiss-Prot Reviewed
331
989TNCtenascin C9Clinical TrialsOMIM Disease Gene
331
990WDR5WD repeat domain 59Highly ConstrainedTrending
331
991WWOXWW domain containing oxidoreductase16Tumor SuppressorOMIM Disease Gene
331
992EHMT2euchromatic histone lysine methyltransferase 26TrendingExperimental GO Evidence
330
993PSMC3proteasome 26S subunit, ATPase 311FDA Approved TargetOMIM Disease Gene
330
994RPL7ribosomal protein L78Highly ConstrainedFDA Approved Target
330
995MSNmoesinXHighly ConstrainedOMIM Disease Gene
329
996NDRG1N-myc downstream regulated 18OMIM Disease GeneTrending
329
997SLC7A5solute carrier family 7 member 516TransporterTrending
329
998ETV6ETS variant transcription factor 612OncogeneOMIM Disease Gene
328
999RBBP7RB binding protein 7, chromatin remodeling factorXHighly ConstrainedOMIM Disease Gene
328
1000SRSF2serine and arginine rich splicing factor 217Experimental GO EvidenceSwiss-Prot Reviewed
328