Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

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9511,000 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
951POMCproopiomelanocortin2Hub GeneOMIM Disease Gene
339
952CCT4chaperonin containing TCP1 subunit 42Hub GeneHighly Studied
338
953CXCR3C-X-C motif chemokine receptor 3XHub GeneReceptor
338
954IGF2Rinsulin like growth factor 2 receptor6ReceptorTransporter
338
955OLR1oxidized low density lipoprotein receptor 112ReceptorHighly Studied
338
956PSMC2proteasome 26S subunit, ATPase 27Highly ConstrainedHub Gene
338
957YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta22Highly StudiedTrending
338
958ALOX5arachidonate 5-lipoxygenase10FDA Approved TargetHighly Studied
337
959L1CAML1 cell adhesion moleculeXHighly ConstrainedOMIM Disease Gene
337
960PECAM1platelet and endothelial cell adhesion molecule 117Hub GeneHighly Studied
337
961PLA2G7phospholipase A2 group VII6Hub GeneClinical Trials
337
962ANGPT1angiopoietin 18Clinical TrialsOMIM Disease Gene
336
963CBX3chromobox 37Hub GeneHighly Studied
336
964PTK2Bprotein tyrosine kinase 2 beta8Hub GeneKinase
336
965CD81CD81 molecule11Hub GeneReceptor
335
966IL1R1interleukin 1 receptor type 12Hub GeneReceptor
335
967NKX2-1NK2 homeobox 114Transcription FactorOMIM Disease Gene
335
968SETSET nuclear proto-oncogene9Highly ConstrainedOncogene
335
969SFNstratifin1Hub GeneHighly Studied
335
970PGK1phosphoglycerate kinase 1XHighly ConstrainedHub Gene
334
971RPS19ribosomal protein S1919Highly ConstrainedHub Gene
334
972SDHBsuccinate dehydrogenase complex iron sulfur subunit B1Hub GeneTransporter
334
973TSLPthymic stromal lymphopoietin5Hub GeneFDA Approved Target
334
974AVParginine vasopressin20OMIM Disease GeneHighly Studied
333
975CCN1cellular communication network factor 11Highly StudiedExperimental GO Evidence
333
976HADHAhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha2OMIM Disease GeneHighly Studied
333
977RPL7Aribosomal protein L7a9Highly ConstrainedHub Gene
333
978APLNapelinXExperimental GO EvidenceSwiss-Prot Reviewed
332
979ATXN3ataxin 314ProteaseOMIM Disease Gene
332
980LIPClipase C, hepatic type15Hub GeneOMIM Disease Gene
332
981RPS8ribosomal protein S81Highly ConstrainedHub Gene
332
982SOSTsclerostin17FDA Approved TargetOMIM Disease Gene
332
983CCT6Achaperonin containing TCP1 subunit 6A7Highly ConstrainedHub Gene
331
984MAP3K5mitogen-activated protein kinase kinase kinase 56Hub GeneKinase
331
985RPL6ribosomal protein L612Highly ConstrainedHub Gene
331
986RPS4Xribosomal protein S4 X-linkedXHub GeneFDA Approved Target
331
987SLC26A4solute carrier family 26 member 47TransporterOMIM Disease Gene
331
988TMPOthymopoietin12Experimental GO EvidenceSwiss-Prot Reviewed
331
989TNCtenascin C9Clinical TrialsOMIM Disease Gene
331
990WDR5WD repeat domain 59Highly ConstrainedHub Gene
331
991WWOXWW domain containing oxidoreductase16Tumor SuppressorOMIM Disease Gene
331
992EHMT2euchromatic histone lysine methyltransferase 26Hub GeneTrending
330
993PSMC3proteasome 26S subunit, ATPase 311Hub GeneFDA Approved Target
330
994RPL7ribosomal protein L78Highly ConstrainedHub Gene
330
995MSNmoesinXHighly ConstrainedHub Gene
329
996NDRG1N-myc downstream regulated 18OMIM Disease GeneTrending
329
997SLC7A5solute carrier family 7 member 516TransporterTrending
329
998ETV6ETS variant transcription factor 612OncogeneOMIM Disease Gene
328
999RBBP7RB binding protein 7, chromatin remodeling factorXHighly ConstrainedHub Gene
328
1000SRSF2serine and arginine rich splicing factor 217Hub GeneExperimental GO Evidence
328