Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

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1,0011,050 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
1001STAT5Bsignal transducer and activator of transcription 5B17Highly ConstrainedOMIM Disease Gene
328
1002ARF6ARF GTPase 614Highly ConstrainedTransporter
327
1003EIF4EBP1eukaryotic translation initiation factor 4E binding protein 18Experimental GO EvidenceSwiss-Prot Reviewed
327
1004FABP4fatty acid binding protein 48TransporterExperimental GO Evidence
327
1005ATF3activating transcription factor 31Transcription FactorTrending
326
1006PSMC4proteasome 26S subunit, ATPase 419FDA Approved TargetExperimental GO Evidence
326
1007ERN1endoplasmic reticulum to nucleus signaling 117KinaseExperimental GO Evidence
325
1008GATA1GATA binding protein 1XHighly ConstrainedTranscription Factor
325
1009GATA4GATA binding protein 48Transcription FactorOMIM Disease Gene
325
1010HK2hexokinase 22KinaseExperimental GO Evidence
325
1011KRT8keratin 812OMIM Disease GeneTrending
325
1012NUP98nucleoporin 98 and 96 precursor11Highly ConstrainedProtease
325
1013PTCH1patched 19Highly ConstrainedReceptor
325
1014SRSF3serine and arginine rich splicing factor 36Highly ConstrainedTransporter
325
1015ARRB1arrestin beta 111TransporterExperimental GO Evidence
324
1016CUL4Bcullin 4BXDNA RepairHighly Constrained
324
1017LRP5LDL receptor related protein 511ReceptorOMIM Disease Gene
324
1018MFN2mitofusin 21OMIM Disease GeneTrending
324
1019PHGDHphosphoglycerate dehydrogenase1OMIM Disease GeneTrending
324
1020PSMD1proteasome 26S subunit, non-ATPase 12Highly ConstrainedFDA Approved Target
324
1021SPHK1sphingosine kinase 117KinaseTrending
324
1022TLN1talin 19Highly ConstrainedTrending
324
1023UBBubiquitin B17TrendingExperimental GO Evidence
324
1024ULK1unc-51 like autophagy activating kinase 112KinaseTrending
324
1025A2Malpha-2-macroglobulin12FDA Approved TargetExperimental GO Evidence
323
1026ABCA4ATP binding cassette subfamily A member 41TransporterOMIM Disease Gene
323
1027EEF1Geukaryotic translation elongation factor 1 gamma11Experimental GO EvidenceSwiss-Prot Reviewed
323
1028PAHphenylalanine hydroxylase12FDA Approved TargetOMIM Disease Gene
323
1029TERF2telomeric repeat binding factor 216TrendingExperimental GO Evidence
323
1030CD24CD24 molecule6OMIM Disease GeneTrending
322
1031EIF3Aeukaryotic translation initiation factor 3 subunit A10Highly ConstrainedExperimental GO Evidence
322
1032F10coagulation factor X13ProteaseFDA Approved Target
322
1033TGFBItransforming growth factor beta induced5OMIM Disease GeneExperimental GO Evidence
322
1034TPM1tropomyosin 115OMIM Disease GeneVariant-Rich
322
1035U2AF2U2 small nuclear RNA auxiliary factor 219Highly ConstrainedOMIM Disease Gene
322
1036AXIN1axin 116Tumor SuppressorOMIM Disease Gene
321
1037CCR7C-C motif chemokine receptor 717ReceptorExperimental GO Evidence
321
1038RPN1ribophorin I3Highly ConstrainedTrending
321
1039SLC4A1solute carrier family 4 member 1 (Diego blood group)17TransporterOMIM Disease Gene
321
1040UBR5ubiquitin protein ligase E3 component n-recognin 58DNA RepairHighly Constrained
321
1041IGFBP1insulin like growth factor binding protein 17Experimental GO EvidenceSwiss-Prot Reviewed
320
1042ITGB4integrin subunit beta 417ReceptorOMIM Disease Gene
320
1043KRT5keratin 512OMIM Disease GeneVariant-Rich
320
1044LEF1lymphoid enhancer binding factor 14Transcription FactorOMIM Disease Gene
320
1045NR1H4nuclear receptor subfamily 1 group H member 412ReceptorFDA Approved Target
320
1046PRKCIprotein kinase C iota3KinaseOncogene
320
1047PSMA6proteasome 20S subunit alpha 614Highly ConstrainedFDA Approved Target
320
1048CBX5chromobox 512TrendingExperimental GO Evidence
319
1049DLG1discs large MAGUK scaffold protein 13Experimental GO EvidenceSwiss-Prot Reviewed
319
1050GPER1G protein-coupled estrogen receptor 17ReceptorExperimental GO Evidence
319