Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
51–100 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
51CXCR4C-X-C motif chemokine receptor 42Hub GeneReceptor
2,177
52IFNGinterferon gamma12ApoptosisHub Gene
2,159
53TERTtelomerase reverse transcriptase5Hub GeneFDA Approved Target
2,102
54COMTcatechol-O-methyltransferase22Hub GeneFDA Approved Target
2,076
55IGF1insulin like growth factor 112Hub GeneClinical Trials
2,076
56CD4CD4 molecule12Hub GeneReceptor
2,026
57MMP2matrix metallopeptidase 216Hub GeneProtease
1,979
58CFTRCF transmembrane conductance regulator7Ion ChannelTransporter
1,945
59LEPleptin7Hub GeneOMIM Disease Gene
1,912
60NFE2L2NFE2 like bZIP transcription factor 22Hub GeneTranscription Factor
1,912
61GSTT1glutathione S-transferase theta 122Highly StudiedExperimental GO Evidence
1,901
62CDKN1Acyclin dependent kinase inhibitor 1A6Hub GeneHighly Studied
1,844
63SIRT1sirtuin 110Hub GeneClinical Trials
1,824
64JAK2Janus kinase 29ApoptosisHub Gene
1,812
65CCND1cyclin D111Hub GeneOncogene
1,795
66ACE2angiotensin converting enzyme 2XHub GeneProtease
1,724
67GSTP1glutathione S-transferase pi 111Hub GeneClinical Trials
1,723
68PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha3Highly ConstrainedHub Gene
1,720
69RELARELA proto-oncogene, NF-kB subunit11Hub GeneTranscription Factor
1,681
70HLA-Amajor histocompatibility complex, class I, A6Hub GeneHighly Studied
1,676
71IL17Ainterleukin 17A6Hub GeneFDA Approved Target
1,654
72CCR5C-C motif chemokine receptor 53Hub GeneReceptor
1,643
73CCL2C-C motif chemokine ligand 217Hub GeneClinical Trials
1,641
74TLR2toll like receptor 24Hub GeneReceptor
1,622
75NOTCH1notch receptor 19Highly ConstrainedHub Gene
1,592
76PARP1poly(ADP-ribose) polymerase 11ApoptosisDNA Repair
1,590
77ATMATM serine/threonine kinase11Homologous RecombinationHub Gene
1,575
78GSK3Bglycogen synthase kinase 3 beta3Hub GeneKinase
1,556
79HLA-DQB1major histocompatibility complex, class II, DQ beta 16Highly StudiedExperimental GO Evidence
1,556
80EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit7Highly ConstrainedHub Gene
1,553
81SERPINE1serpin family E member 17Hub GeneEarly Pipeline
1,549
82YAP1Yes1 associated transcriptional regulator11Highly ConstrainedHub Gene
1,515
83SRCSRC proto-oncogene, non-receptor tyrosine kinase20Hub GeneKinase
1,512
84ITGB1integrin subunit beta 110Hub GeneReceptor
1,502
85HMGB1high mobility group box 113DNA RepairHighly Constrained
1,499
86MAPK3mitogen-activated protein kinase 316Hub GeneKinase
1,495
87F2coagulation factor II, thrombin11Hub GeneProtease
1,489
88CD44CD44 molecule (IN blood group)11Hub GeneReceptor
1,488
89CXCL12C-X-C motif chemokine ligand 1210Hub GeneHighly Studied
1,470
90MAPK14mitogen-activated protein kinase 146Hub GeneKinase
1,465
91RB1RB transcriptional corepressor 113Highly ConstrainedHub Gene
1,423
92METMET proto-oncogene, receptor tyrosine kinase7Hub GeneKinase
1,418
93HSP90AA1heat shock protein 90 alpha family class A member 114Hub GeneClinical Trials
1,403
94EP300EP300 lysine acetyltransferase22ApoptosisHighly Constrained
1,399
95UBCubiquitin C12Hub GeneHighly Studied
1,371
96BIRC5baculoviral IAP repeat containing 517Hub GeneClinical Trials
1,364
97ICAM1intercellular adhesion molecule 119Hub GeneReceptor
1,358
98XRCC1X-ray repair cross complementing 119DNA RepairHub Gene
1,347
99F5coagulation factor V1FDA Approved TargetOMIM Disease Gene
1,344
100SP1Sp1 transcription factor12Highly ConstrainedHub Gene
1,341