51–100 of 20,598 genesranked by Most Researched

#	Gene	Name	Chr	Tags	PubMed Papers
51	CXCR4	C-X-C motif chemokine receptor 4	2	ReceptorFDA Approved Target	2,177
52	IFNG	interferon gamma	12	ApoptosisFDA Approved Target	2,159
53	TERT	telomerase reverse transcriptase	5	FDA Approved TargetOMIM Disease Gene	2,102
54	COMT	catechol-O-methyltransferase	22	FDA Approved TargetOMIM Disease Gene	2,076
55	IGF1	insulin like growth factor 1	12	Clinical TrialsOMIM Disease Gene	2,076
56	CD4	CD4 molecule	12	ReceptorFDA Approved Target	2,026
57	MMP2	matrix metallopeptidase 2	16	ProteaseClinical Trials	1,979
58	CFTR	CF transmembrane conductance regulator	7	Ion ChannelTransporter	1,945
59	LEP	leptin	7	OMIM Disease GeneHighly Studied	1,912
60	NFE2L2	NFE2 like bZIP transcription factor 2	2	Transcription FactorFDA Approved Target	1,912
61	GSTT1	glutathione S-transferase theta 1	22	Highly StudiedExperimental GO Evidence	1,901
62	CDKN1A	cyclin dependent kinase inhibitor 1A	6	Highly StudiedExperimental GO Evidence	1,844
63	SIRT1	sirtuin 1	10	Clinical TrialsHighly Studied	1,824
64	JAK2	Janus kinase 2	9	ApoptosisKinase	1,812
65	CCND1	cyclin D1	11	OncogeneFDA Approved Target	1,795
66	ACE2	angiotensin converting enzyme 2	X	ProteaseReceptor	1,724
67	GSTP1	glutathione S-transferase pi 1	11	Clinical TrialsHighly Studied	1,723
68	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	3	Highly ConstrainedKinase	1,720
69	RELA	RELA proto-oncogene, NF-kB subunit	11	Transcription FactorClinical Trials	1,681
70	HLA-A	major histocompatibility complex, class I, A	6	Highly StudiedExperimental GO Evidence	1,676
71	IL17A	interleukin 17A	6	FDA Approved TargetHighly Studied	1,654
72	CCR5	C-C motif chemokine receptor 5	3	ReceptorFDA Approved Target	1,643
73	CCL2	C-C motif chemokine ligand 2	17	Clinical TrialsHighly Studied	1,641
74	TLR2	toll like receptor 2	4	ReceptorClinical Trials	1,622
75	NOTCH1	notch receptor 1	9	Highly ConstrainedReceptor	1,592
76	PARP1	poly(ADP-ribose) polymerase 1	1	ApoptosisDNA Repair	1,590
77	ATM	ATM serine/threonine kinase	11	Homologous RecombinationKinase	1,575
78	GSK3B	glycogen synthase kinase 3 beta	3	KinaseFDA Approved Target	1,556
79	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	Highly StudiedExperimental GO Evidence	1,556
80	EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit	7	Highly ConstrainedFDA Approved Target	1,553
81	SERPINE1	serpin family E member 1	7	Early PipelineOMIM Disease Gene	1,549
82	YAP1	Yes1 associated transcriptional regulator	11	Highly ConstrainedOncogene	1,515
83	SRC	SRC proto-oncogene, non-receptor tyrosine kinase	20	KinaseOncogene	1,512
84	ITGB1	integrin subunit beta 1	10	ReceptorFDA Approved Target	1,502
85	HMGB1	high mobility group box 1	13	DNA RepairHighly Constrained	1,499
86	MAPK3	mitogen-activated protein kinase 3	16	KinaseClinical Trials	1,495
87	F2	coagulation factor II, thrombin	11	ProteaseFDA Approved Target	1,489
88	CD44	CD44 molecule (IN blood group)	11	ReceptorEarly Pipeline	1,488
89	CXCL12	C-X-C motif chemokine ligand 12	10	Clinical TrialsHighly Studied	1,470
90	MAPK14	mitogen-activated protein kinase 14	6	KinaseClinical Trials	1,465
91	RB1	RB transcriptional corepressor 1	13	Highly ConstrainedTumor Suppressor	1,423
92	MET	MET proto-oncogene, receptor tyrosine kinase	7	KinaseOncogene	1,418
93	HSP90AA1	heat shock protein 90 alpha family class A member 1	14	Clinical TrialsHighly Studied	1,403
94	EP300	EP300 lysine acetyltransferase	22	ApoptosisHighly Constrained	1,399
95	UBC	ubiquitin C	12	Highly StudiedExperimental GO Evidence	1,371
96	BIRC5	baculoviral IAP repeat containing 5	17	Clinical TrialsHighly Studied	1,364
97	ICAM1	intercellular adhesion molecule 1	19	ReceptorClinical Trials	1,358
98	XRCC1	X-ray repair cross complementing 1	19	DNA RepairOMIM Disease Gene	1,347
99	F5	coagulation factor V	1	FDA Approved TargetOMIM Disease Gene	1,344
100	SP1	Sp1 transcription factor	12	Highly ConstrainedTranscription Factor	1,341