Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
Showing 51100 of 20,598 genes
#GeneNameChrTagsPubMedPubMed Papers
51CXCR4C-X-C motif chemokine receptor 42Hub GeneReceptor2,1772,177
52IFNGinterferon gamma12ApoptosisHub Gene2,1592,159
53TERTtelomerase reverse transcriptase5Hub GeneFDA Approved Target2,1022,102
54COMTcatechol-O-methyltransferase22Hub GeneFDA Approved Target2,0762,076
55IGF1insulin like growth factor 112Hub GeneClinical Trials2,0762,076
56CD4CD4 molecule12Hub GeneReceptor2,0262,026
57MMP2matrix metallopeptidase 216Hub GeneProtease1,9791,979
58CFTRCF transmembrane conductance regulator7Ion ChannelTransporter1,9451,945
59LEPleptin7Hub GeneOMIM Disease Gene1,9121,912
60NFE2L2NFE2 like bZIP transcription factor 22Hub GeneTranscription Factor1,9121,912
61GSTT1glutathione S-transferase theta 122Highly StudiedExperimental GO Evidence1,9011,901
62CDKN1Acyclin dependent kinase inhibitor 1A6Hub GeneHighly Studied1,8441,844
63SIRT1sirtuin 110Hub GeneTranscription Factor1,8241,824
64JAK2Janus kinase 29ApoptosisHub Gene1,8121,812
65CCND1cyclin D111Hub GeneOncogene1,7951,795
66ACE2angiotensin converting enzyme 2XHub GeneProtease1,7241,724
67GSTP1glutathione S-transferase pi 111Hub GeneClinical Trials1,7231,723
68PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha3Highly ConstrainedHub Gene1,7201,720
69RELARELA proto-oncogene, NF-kB subunit11Hub GeneTranscription Factor1,6811,681
70HLA-Amajor histocompatibility complex, class I, A6Hub GeneHighly Studied1,6761,676
71IL17Ainterleukin 17A6Hub GeneFDA Approved Target1,6541,654
72CCR5C-C motif chemokine receptor 53Hub GeneReceptor1,6431,643
73CCL2C-C motif chemokine ligand 217Hub GeneClinical Trials1,6411,641
74TLR2toll like receptor 24Hub GeneReceptor1,6221,622
75NOTCH1notch receptor 19Highly ConstrainedHub Gene1,5921,592
76PARP1poly(ADP-ribose) polymerase 11ApoptosisDNA Repair1,5901,590
77ATMATM serine/threonine kinase11Homologous RecombinationHub Gene1,5751,575
78GSK3Bglycogen synthase kinase 3 beta3Hub GeneKinase1,5561,556
79HLA-DQB1major histocompatibility complex, class II, DQ beta 16Highly StudiedTrending1,5561,556
80EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit7Highly ConstrainedHub Gene1,5531,553
81SERPINE1serpin family E member 17Hub GeneEarly Pipeline1,5491,549
82YAP1Yes1 associated transcriptional regulator11Highly ConstrainedHub Gene1,5151,515
83SRCSRC proto-oncogene, non-receptor tyrosine kinase20Hub GeneKinase1,5121,512
84ITGB1integrin subunit beta 110Hub GeneReceptor1,5021,502
85HMGB1high mobility group box 113DNA RepairHighly Constrained1,4991,499
86MAPK3mitogen-activated protein kinase 316Hub GeneKinase1,4951,495
87F2coagulation factor II, thrombin11Hub GeneProtease1,4891,489
88CD44CD44 molecule (IN blood group)11Hub GeneReceptor1,4881,488
89CXCL12C-X-C motif chemokine ligand 1210Hub GeneHighly Studied1,4701,470
90MAPK14mitogen-activated protein kinase 146Hub GeneKinase1,4651,465
91RB1RB transcriptional corepressor 113Highly ConstrainedHub Gene1,4231,423
92METMET proto-oncogene, receptor tyrosine kinase7Hub GeneKinase1,4181,418
93HSP90AA1heat shock protein 90 alpha family class A member 114Hub GeneClinical Trials1,4031,403
94EP300EP300 lysine acetyltransferase22ApoptosisHighly Constrained1,3991,399
95UBCubiquitin C12Hub GeneHighly Studied1,3711,371
96BIRC5baculoviral IAP repeat containing 517Hub GeneTranscription Factor1,3641,364
97ICAM1intercellular adhesion molecule 119Hub GeneReceptor1,3581,358
98XRCC1X-ray repair cross complementing 119DNA RepairHub Gene1,3471,347
99F5coagulation factor V1FDA Approved TargetOMIM Disease Gene1,3441,344
100SP1Sp1 transcription factor12Highly ConstrainedHub Gene1,3411,341