Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
101–150 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
101RAC1Rac family small GTPase 17Highly ConstrainedHub Gene
1,340
102CTLA4cytotoxic T-lymphocyte associated protein 42Highly ConstrainedHub Gene
1,338
103HDAC1histone deacetylase 11Hub GeneFDA Approved Target
1,335
104SOD1superoxide dismutase 121Hub GeneFDA Approved Target
1,328
105JUNJun proto-oncogene, AP-1 transcription factor subunit1Hub GeneOncogene
1,326
106DRD2dopamine receptor D211Hub GeneReceptor
1,325
107IL4interleukin 45Hub GeneClinical Trials
1,301
108NLRP3NLR family pyrin domain containing 31Hub GeneOMIM Disease Gene
1,292
109NR3C1nuclear receptor subfamily 3 group C member 15Highly ConstrainedHub Gene
1,291
110PON1paraoxonase 17OMIM Disease GeneHighly Studied
1,282
111ESR2estrogen receptor 214Hub GeneReceptor
1,277
112IGF1Rinsulin like growth factor 1 receptor15Hub GeneKinase
1,269
113FASFas cell surface death receptor10ApoptosisReceptor
1,259
114CASP3caspase 34ApoptosisHub Gene
1,254
115PDCD1programmed cell death 12Hub GeneOMIM Disease Gene
1,253
116CAV1caveolin 17Hub GeneOMIM Disease Gene
1,228
117ITGB3integrin subunit beta 317Hub GeneReceptor
1,223
118CDK1cyclin dependent kinase 110Hub GeneKinase
1,209
119HMOX1heme oxygenase 122Hub GeneOMIM Disease Gene
1,204
120SPP1secreted phosphoprotein 14Hub GeneClinical Trials
1,203
121IL18interleukin 1811Hub GeneClinical Trials
1,189
122KITKIT proto-oncogene, receptor tyrosine kinase4Highly ConstrainedHub Gene
1,173
123FOXP3forkhead box P3XHighly ConstrainedHub Gene
1,170
124NPM1nucleophosmin 15DNA RepairHighly Constrained
1,170
125RHOAras homolog family member A3Hub GeneOncogene
1,169
126HSPA5heat shock protein family A (Hsp70) member 59Hub GeneHighly Studied
1,168
127AGTangiotensinogen1Hub GeneClinical Trials
1,161
128STAT1signal transducer and activator of transcription 12Highly ConstrainedHub Gene
1,153
129NPPBnatriuretic peptide B1Highly StudiedExperimental GO Evidence
1,148
130ADRB2adrenoceptor beta 25Hub GeneReceptor
1,129
131APOA1apolipoprotein A111Hub GeneTransporter
1,127
132BAXBCL2 associated X, apoptosis regulator19ApoptosisHub Gene
1,121
133CYP1A1cytochrome P450 family 1 subfamily A member 115Hub GeneHighly Studied
1,117
134CYP2C19cytochrome P450 family 2 subfamily C member 1910Hub GeneHighly Studied
1,111
135HLA-Cmajor histocompatibility complex, class I, C6Hub GeneOMIM Disease Gene
1,109
136MLH1mutL homolog 13DNA RepairHub Gene
1,109
137CDKN1Bcyclin dependent kinase inhibitor 1B12Hub GeneTumor Suppressor
1,107
138LRRK2leucine rich repeat kinase 212Hub GeneKinase
1,107
139KDRkinase insert domain receptor4Highly ConstrainedHub Gene
1,104
140TARDBPTAR DNA binding protein1Highly ConstrainedHub Gene
1,097
141PTK2protein tyrosine kinase 28Hub GeneKinase
1,096
142CYP2D6cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)22Hub GeneHighly Studied
1,089
143LMNAlamin A/C1OMIM Disease GeneHighly Studied
1,085
144LGALS3galectin 314Hub GeneClinical Trials
1,064
145SQSTM1sequestosome 15Hub GeneOMIM Disease Gene
1,058
146MAPK8mitogen-activated protein kinase 810Hub GeneKinase
1,055
147FTOFTO alpha-ketoglutarate dependent dioxygenase16Clinical TrialsOMIM Disease Gene
1,051
148IL1RNinterleukin 1 receptor antagonist2OMIM Disease GeneHighly Studied
1,050
149INSinsulin11Hub GeneOMIM Disease Gene
1,033
150VWFvon Willebrand factor12Hub GeneFDA Approved Target
1,033