Most Researched

Genes ranked by total PubMed publication count — the most-studied genes in biology.

Filter by chromosome
151–200 of 20,598 genesranked by Most Researched
#GeneNameChrTagsPubMed Papers
151SMAD3SMAD family member 315Hub GeneTranscription Factor
1,028
152AGERadvanced glycosylation end-product specific receptor6DNA RepairReceptor
1,026
153MKI67marker of proliferation Ki-6710Hub GeneHighly Studied
1,023
154APCAPC regulator of Wnt signaling pathway5Highly ConstrainedHub Gene
1,021
155MMP1matrix metallopeptidase 111ProteaseFDA Approved Target
1,020
156CREBBPCREB binding lysine acetyltransferase16Highly ConstrainedHub Gene
1,012
157IL1Ainterleukin 1 alpha2Hub GeneFDA Approved Target
1,009
158HFEhomeostatic iron regulator6TransporterOMIM Disease Gene
1,001
159NOD2nucleotide binding oligomerization domain containing 216Hub GeneFDA Approved Target
1,001
160AGTR1angiotensin II receptor type 13ReceptorFDA Approved Target
997
161RETret proto-oncogene10Highly ConstrainedHub Gene
995
162PCNAproliferating cell nuclear antigen20DNA RepairHub Gene
991
163HSPA8heat shock protein family A (Hsp70) member 811Highly ConstrainedHub Gene
990
164PRKNparkin RBR E3 ubiquitin protein ligase6Hub GeneOMIM Disease Gene
989
165SOD2superoxide dismutase 26Hub GeneOMIM Disease Gene
985
166IDH1isocitrate dehydrogenase (NADP(+)) 12Hub GeneFDA Approved Target
984
167CASP8caspase 82ApoptosisHub Gene
980
168HLA-Gmajor histocompatibility complex, class I, G6Highly StudiedExperimental GO Evidence
980
169PRKCAprotein kinase C alpha17Hub GeneKinase
978
170CYP2C9cytochrome P450 family 2 subfamily C member 910Hub GeneHighly Studied
971
171E2F1E2F transcription factor 120Hub GeneTranscription Factor
969
172CYP3A4cytochrome P450 family 3 subfamily A member 47Hub GeneFDA Approved Target
965
173TP63tumor protein p633Highly ConstrainedTranscription Factor
965
174MUC1mucin 1, cell surface associated1Hub GeneTumor Suppressor
960
175APOBapolipoprotein B2Hub GeneTransporter
954
176GRB2growth factor receptor bound protein 217Highly ConstrainedHub Gene
953
177VIMvimentin10Clinical TrialsOMIM Disease Gene
949
178ABCG2ATP binding cassette subfamily G member 2 (JR blood group)4TransporterHighly Studied
944
179HSPA4heat shock protein family A (Hsp70) member 45Highly ConstrainedHub Gene
944
180PTPN11protein tyrosine phosphatase non-receptor type 1112Highly ConstrainedHub Gene
943
181MSH2mutS homolog 22DNA RepairHub Gene
937
182CSNK2A1casein kinase 2 alpha 120Highly ConstrainedKinase
936
183RUNX1RUNX family transcription factor 121Hub GeneOncogene
935
184CDK2cyclin dependent kinase 212DNA RepairHub Gene
930
185TNFSF10TNF superfamily member 103Highly StudiedExperimental GO Evidence
928
186EDN1endothelin 16Hub GeneOMIM Disease Gene
927
187PLK1polo like kinase 116Highly ConstrainedHub Gene
927
188FMR1fragile X messenger ribonucleoprotein 1XDNA RepairHub Gene
923
189ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit19ApoptosisDNA Repair
921
190GHRLghrelin and obestatin prepropeptide3Hub GeneHighly Studied
920
191VHLvon Hippel-Lindau tumor suppressor3Hub GeneTumor Suppressor
919
192ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase9DNA RepairHighly Constrained
918
193SMAD4SMAD family member 418Highly ConstrainedHub Gene
915
194PRKDCprotein kinase, DNA-activated, catalytic subunit8DNA RepairHighly Constrained
913
195IL2interleukin 24Hub GeneOncogene
900
196LCN2lipocalin 29TransporterHighly Studied
896
197LDLRlow density lipoprotein receptor19ReceptorTransporter
893
198MIFmacrophage migration inhibitory factor22OMIM Disease GeneHighly Studied
891
199CFHcomplement factor H1OMIM Disease GeneHighly Studied
890
200DNMT1DNA methyltransferase 119Highly ConstrainedHub Gene
879