2 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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6PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITYβ Swiss-Prot Reviewed
refractive errorneurodegenerative diseaseidiopathic pulmonary fibrosisAbnormality of refraction
Based on limited published evidence, CDRT15 is a gene identified within the 1.4-Mb CMT1A/HNPP duplicated region on chromosome 17 1. Originally discovered during characterization of this genomic region, CDRT15's specific molecular function remains largely uncharacterized in standard databases. Recent bioinformatic analysis suggests potential involvement in cholangiocarcinoma pathogenesis, with CDRT15 overexpression associated with poor prognosis and immune/inflammatory responses in cancer tissues 2. However, mechanistic understanding of CDRT15 function requires further investigation beyond these limited studies.
1
CDRT15 identified as a new gene within the 1.4-Mb CMT1A duplicated region; primarily established in context of genomic rearrangement characterization
PMID: 113810292
CDRT15 overexpressed in cholangiocarcinoma; associated with poor prognosis and immune/inflammatory response pathways
PMID: 37543771β Limited data available β This gene has 2 indexed publications. Summary and analysis may be incomplete.
refractive errorOpen Targets
neurodegenerative diseaseOpen Targets
idiopathic pulmonary fibrosisOpen Targets
Abnormality of refractionOpen Targets
Abruptio PlacentaeOpen Targets
cholangiocarcinomaOpen Targets
glomerulonephritisOpen Targets
retinal degenerationOpen Targets
paralytic strabismusOpen Targets
post term pregnancyOpen Targets
Fuchs endothelial corneal dystrophyOpen Targets
Fuchs' endothelial dystrophyOpen Targets
adolescent idiopathic scoliosisOpen Targets
cutaneous melanomaOpen Targets
ocular hypotensionOpen Targets
response to antihypertensive drugOpen Targets
diabetes mellitusOpen Targets
self-injurious ideationOpen Targets
No pathogenic variants reported on ClinVar for this gene.