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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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CFAP107
cilia and flagella associated protein 107
Chromosome 1 Β· 1p36.21
NCBI Gene: 93190Ensembl: ENSG00000157330.10HGNC: HGNC:28567UniProt: Q5VUY5
7PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
axonemal microtubuleflagellated sperm motilitysperm flagellumaxonemal A tubule inner sheathcentral nervous system cancerCrigler-Najjar syndrome type 2transient familial neonatal hyperbilirubinemiacolorectal adenocarcinoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

cilia and flagella associated protein 107

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
central nervous system cancerOpen Targets
0.05Suggestive
Crigler-Najjar syndrome type 2Open Targets
0.04Suggestive
transient familial neonatal hyperbilirubinemiaOpen Targets
0.04Suggestive
colorectal adenocarcinomaOpen Targets
0.04Suggestive
psoriasisOpen Targets
0.02Suggestive
ependymomaOpen Targets
0.02Suggestive
squamous cell carcinomaOpen Targets
0.01Suggestive
childhood supratentorial ependymomaOpen Targets
0.01Suggestive
papillary thyroid carcinomaOpen Targets
0.01Suggestive
nasopharyngeal neoplasmOpen Targets
0.00Suggestive
breast cancerOpen Targets
0.00Suggestive
hepatocellular carcinomaOpen Targets
0.00Suggestive
endometrial carcinomaOpen Targets
0.00Suggestive
sarcoidosisOpen Targets
0.00Suggestive
non-small cell lung carcinomaOpen Targets
0.00Suggestive
chronic rhinosinusitisOpen Targets
0.00Suggestive
meningeal tuberculosisOpen Targets
0.00Suggestive
major depressive disorderOpen Targets
0.00Suggestive
lung cancerOpen Targets
0.00Suggestive
Uterine CarcinosarcomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
SPEM3Shared pathway100%TEKTIP1Shared pathway100%CFAP144Shared pathway100%CIMIP2AShared pathway100%CFAP77Shared pathway100%SPMIP10Shared pathway100%
Tissue Expression6 tissues
Lung
100%
Brain
71%
Liver
29%
Ovary
21%
Bone Marrow
7%
Heart
0%
Gene Interaction Network
Click a node to explore
CFAP107SPEM3TEKTIP1CFAP144CIMIP2ACFAP77SPMIP10
PROTEIN STRUCTURE
Preparing viewer…
PDB7UNG Β· 3.60 Γ… Β· EM
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.53LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.99 [0.65–1.53]
RankingsWhere CFAP107 stands among ~20K protein-coding genes
  • #17,800of 20,598
    Most Researched7
  • #15,377of 17,882
    Most Constrained (LOEUF)1.53
Genes detectedCFAP107
Sources retrieved0 papers
Response timeβ€”