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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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CFAP73
cilia and flagella associated protein 73
Chromosome 12 Β· 12q24.13
NCBI Gene: 387885Ensembl: ENSG00000186710.13HGNC: HGNC:37100UniProt: A6NFT4
5PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
motile ciliumaxonemal doublet microtubuleinner dynein arm assemblycilium movementdementiacoronary artery diseasegouttype 1 diabetes mellitus
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

cilia and flagella associated protein 73

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
dementiaOpen Targets
0.04Suggestive
coronary artery diseaseOpen Targets
0.03Suggestive
goutOpen Targets
0.03Suggestive
type 1 diabetes mellitusOpen Targets
0.03Suggestive
hypothyroidismOpen Targets
0.03Suggestive
strokeOpen Targets
0.03Suggestive
esophageal carcinomaOpen Targets
0.03Suggestive
myocardial infarctionOpen Targets
0.03Suggestive
crush injuryOpen Targets
0.03Suggestive
placenta praeviaOpen Targets
0.03Suggestive
sialadenitisOpen Targets
0.02Suggestive
thyroid diseaseOpen Targets
0.02Suggestive
Abnormality of the skeletal systemOpen Targets
0.02Suggestive
Graves diseaseOpen Targets
0.02Suggestive
chronic obstructive pulmonary diseaseOpen Targets
0.02Suggestive
Crohn's diseaseOpen Targets
0.02Suggestive
idiopathic pulmonary fibrosisOpen Targets
0.00Suggestive
Sjogren syndromeOpen Targets
0.00Suggestive
ulcerative colitisOpen Targets
0.00Suggestive
melanomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
DNAAF5Shared pathway67%SPAG6Shared pathway50%DNAH7Shared pathway40%DNAAF6Shared pathway40%DNAH3Shared pathway33%HYDINShared pathway33%
Tissue Expression6 tissues
Bone Marrow
100%
Lung
39%
Liver
15%
Brain
10%
Ovary
10%
Heart
0%
Gene Interaction Network
Click a node to explore
CFAP73DNAAF5SPAG6DNAH7DNAAF6DNAH3HYDIN
PROTEIN STRUCTURE
Preparing viewer…
PDB8J07 Β· 4.10 Γ… Β· EM
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.35LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF1.01 [0.77–1.35]
RankingsWhere CFAP73 stands among ~20K protein-coding genes
  • #18,308of 20,598
    Most Researched5
  • #14,156of 17,882
    Most Constrained (LOEUF)1.35
Genes detectedCFAP73
Sources retrieved0 papers
Response timeβ€”