0 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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29PubMed Papers
20Diseases
3Drugs
0Pathogenic Variants
CLINICALFDA Approved Target
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
enzyme inhibitor activityresponse to hypoxiacellular response to hypoxianegative regulation of mitochondrial electron transport, NADH to ubiquinonetype 2 diabetes mellitusdiabetes mellituspolycystic ovary syndromemetabolic syndrome
AI summary not yet available. Showing NCBI Gene summary.
cytochrome c oxidase hypoxia associated subunit FA4L2
⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
type 2 diabetes mellitusOpen Targets
diabetes mellitusOpen Targets
polycystic ovary syndromeOpen Targets
metabolic syndromeOpen Targets
gestational diabetesOpen Targets
Insulin resistanceOpen Targets
prediabetes syndromeOpen Targets
type 1 diabetes mellitusOpen Targets
Disorder of lipid metabolismOpen Targets
prostate cancerOpen Targets
abnormal glucose toleranceOpen Targets
metabolic diseaseOpen Targets
breast cancerOpen Targets
colorectal cancerOpen Targets
Autosomal dominant polycystic kidney diseaseOpen Targets
chronic kidney diseaseOpen Targets
non-small cell lung carcinomaOpen Targets
No pathogenic variants reported on ClinVar for this gene.
ME-344Phase I/II
Mitochondrial complex I (NADH dehydrogenase) inhibitor
breast cancer
METFORMINApproved
Mitochondrial complex I (NADH dehydrogenase) inhibitor
diabetes mellitus
METFORMIN HYDROCHLORIDEApproved
Mitochondrial complex I (NADH dehydrogenase) inhibitor
type 2 diabetes mellitus