Based on limited published evidence, FHIP2A is a FHF complex subunit required for proper nervous system functioning. FHIP2A functions as a dynein adaptor protein that mediates cargo transport along microtubules through protein-protein interactions 1. Specifically, FHIP2A assembles with FTS and Hook2 to form complexes that colocalize with Rab1A-tagged ER-to-Golgi cargos and facilitate their microtubule-dependent motility 1. FHIP2A also interacts with Rab1 in a membrane-dependent manner to recruit dynein to the ER-Golgi intermediate compartment 2.