2 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
βGeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
41PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITYβ Experimental GO Evidenceβ Swiss-Prot Reviewed
trans-Golgi networktransepithelial transportGolgi apparatusmolecular carrier activityChest painPainbreast cancercancer
Based on limited published evidence, GOLGA1 (golgin A1) is a Golgi apparatus protein with molecular carrier activity that plays important roles in protein trafficking and transport. UniProt annotations indicate it functions in poxvirus morphogenesis by translocating to viral factories to transport membrane fragments and associated proteins to virion assembly sites. GOLGA1 is involved in trans-Golgi network organization and transepithelial transport. Recent evidence suggests GOLGA1 dysregulation in gastroenterological cancers, where it associates with poor patient survival and increased invasiveness through altered protein trafficking 1. GOLGA1 also demonstrates stable expression across diverse tissues and cell types, making it suitable as a housekeeping gene for quantitative studies 2.
1
GOLGA1 plays essential role in protein trafficking within Golgi apparatus and is associated with poor survival rates and increased invasiveness in gastroenterological cancers
PMID: 375084882
GOLGA1 shows stable expression across various tissues and disease states, qualifying as a reliable housekeeping gene for normalization in RNA-based techniques
PMID: 17394773β Limited data available β This gene has 2 indexed publications. Summary and analysis may be incomplete.
breast cancerOpen Targets
lymphatic system diseaseOpen Targets
benign adult familial myoclonic epilepsyOpen Targets
triple-negative breast cancerOpen Targets
Fuchs endothelial corneal dystrophyOpen Targets
Familial ocular anterior segment mesenchymal dysgenesisOpen Targets
Cataract-microcornea syndromeOpen Targets
essential tremorOpen Targets
Cochleosaccular degeneration - cataractOpen Targets
cochleosaccular degeneration-cataract syndromeOpen Targets
Young adult-onset ParkinsonismOpen Targets
X-linked parkinsonism-spasticity syndromeOpen Targets
Spastic paraparesis - deafnessOpen Targets
spastic paraparesis-deafness syndromeOpen Targets
Primary dystonia, DYT13 typeOpen Targets
No pathogenic variants reported on ClinVar for this gene.