1 sources retrieved · Most recent: April 2026 · Index updated 15 days ago
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37PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
protein bindingidentical protein bindingcytoplasmic microtubulecytoplasmtype 2 diabetes mellitusdiabetic nephropathygranuloma annulareprolapse of female genital organ
Based on limited published evidence, GRAMD2B is a GRAM domain-containing protein localized to cytoplasmic microtubules with roles in protein binding and identical protein binding interactions. A genome-wide association study identified a GRAMD2B promoter variant (rs2112481) associated with serum leucocyte concentration in type 1 diabetes 1, suggesting potential involvement in immune-related phenotypes, though the functional mechanism remains undefined.
1
GRAMD2B promoter variant rs2112481 associated with serum leucocyte concentration in type 1 diabetes cohort
PMID: 32077919⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
type 2 diabetes mellitusOpen Targets
diabetic nephropathyOpen Targets
granuloma annulareOpen Targets
prolapse of female genital organOpen Targets
gallbladder diseaseOpen Targets
DNA methylationOpen Targets
smoking initiationOpen Targets
Abnormality of limbsOpen Targets
testicular diseaseOpen Targets
female infertilityOpen Targets
mixed connective tissue diseaseOpen Targets
hyperpituitarismOpen Targets
intestinal diseaseOpen Targets
adverse effectOpen Targets
response to stimulusOpen Targets
hemoglobin D diseaseOpen Targets
hereditary persistence of fetal hemoglobin-sickle cell disease syndromeOpen Targets
No pathogenic variants reported on ClinVar for this gene.