Based on limited published evidence, H3C11 is a histone H3 variant gene located on chromosome 6. H3C11 functions as a core component of nucleosomes, contributing to chr6 structure and gene regulation. In gastric cancer cells, H3C11 expression is downregulated following mebendazole treatment 1. Higher H3C11 expression correlates with decreased overall survival in gastric cancer patients, suggesting a potential role in tumor progression 1. These findings indicate H3C11 may be involved in epigenetic regulation relevant to cancer biology, though further functional characterization is needed.