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0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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HOATZ
HOATZ cilia and flagella associated protein
Chromosome 11 Β· 11q23.1
NCBI Gene: 399949Ensembl: ENSG00000183644.15HGNC: HGNC:25061UniProt: Q6PI97
3PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
spermatogenesisflagellated sperm motilityaxoneme assemblycilium assemblyazoospermiaatherosclerosisspermatogenic failure 51spermatogenic failure 72
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

HOATZ cilia and flagella associated protein

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
azoospermiaOpen Targets
0.09Suggestive
atherosclerosisOpen Targets
0.08Suggestive
spermatogenic failure 51Open Targets
0.07Suggestive
spermatogenic failure 72Open Targets
0.07Suggestive
spermatogenic failure 65Open Targets
0.07Suggestive
spermatogenic failure 84Open Targets
0.07Suggestive
spermatogenic failure 93Open Targets
0.07Suggestive
spermatogenic failure 42Open Targets
0.07Suggestive
spermatogenic failure, X-linked, 3Open Targets
0.07Suggestive
spermatogenic failure 54Open Targets
0.07Suggestive
spermatogenic failure 18Open Targets
0.06Suggestive
spermatogenic failure 27Open Targets
0.06Suggestive
spermatogenic failure 46Open Targets
0.06Suggestive
spermatogenic failure 39Open Targets
0.06Suggestive
spermatogenic failure 56Open Targets
0.06Suggestive
spermatogenic failure 92Open Targets
0.06Suggestive
spermatogenic failure 94Open Targets
0.06Suggestive
spermatogenic failure 20Open Targets
0.06Suggestive
spermatogenic failure 24Open Targets
0.06Suggestive
spermatogenic failure, X-linked, 5Open Targets
0.06Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
TTLL3Shared pathway100%TTLL8Shared pathway75%SPAG16Shared pathway50%TMEM232Shared pathway50%CFAP161Shared pathway50%IQUBShared pathway50%
Tissue Expression6 tissues
Lung
100%
Brain
79%
Ovary
24%
Liver
7%
Bone Marrow
2%
Heart
0%
Gene Interaction Network
Click a node to explore
HOATZTTLL3TTLL8SPAG16TMEM232CFAP161IQUB
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q6PI97
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.37LoF Tolerant
pLIβ“˜
0.02Tolerant
Observed/Expected LoF0.70 [0.38–1.37]
RankingsWhere HOATZ stands among ~20K protein-coding genes
  • #18,874of 20,598
    Most Researched3
  • #14,307of 17,882
    Most Constrained (LOEUF)1.37
Genes detectedHOATZ
Sources retrieved0 papers
Response timeβ€”