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0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
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KRTAP4-1
keratin associated protein 4-1
Chromosome 17 Β· 17q21.2
NCBI Gene: 85285Ensembl: ENSG00000198443.8HGNC: HGNC:18907UniProt: Q9BYQ7
7PubMed Papers
7Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingcytosolkeratin filamentnon-small cell lung carcinomaCrohn's diseaselung canceratopic eczema
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

keratin associated protein 4-1

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜7
non-small cell lung carcinomaOpen Targets
0.04Suggestive
Crohn's diseaseOpen Targets
0.00Suggestive
lung cancerOpen Targets
0.00Suggestive
atopic eczemaOpen Targets
0.00Suggestive
neoplasmOpen Targets
0.00Suggestive
ulcerative colitisOpen Targets
0.00Suggestive
esophageal cancerOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
KRTAP4-3Protein interaction100%KRTAP4-2Protein interaction85%KRTAP2-1Protein interaction83%KRTAP3-1Protein interaction83%KRTAP3-2Protein interaction83%KRTAP9-3Protein interaction83%
Tissue Expression6 tissues
Brain
0%
Bone Marrow
0%
Ovary
0%
Heart
0%
Liver
0%
Lung
0%
Gene Interaction Network
Click a node to explore
KRTAP4-1KRTAP4-3KRTAP4-2KRTAP2-1KRTAP3-1KRTAP3-2KRTAP9-3
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt Q9BYQ7
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.94LoF Tolerant
pLIβ“˜
0.12Tolerant
Observed/Expected LoF2.78 [0.37–1.94]
RankingsWhere KRTAP4-1 stands among ~20K protein-coding genes
  • #17,859of 20,598
    Most Researched7
  • #17,527of 17,882
    Most Constrained (LOEUF)1.94
Genes detectedKRTAP4-1
Sources retrieved0 papers
Response timeβ€”