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0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
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KRTAP4-5
keratin associated protein 4-5
Chromosome 17 Β· 17q21.2
NCBI Gene: 85289Ensembl: ENSG00000198271.5HGNC: HGNC:18899UniProt: Q9BYR2
8PubMed Papers
6Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindinghair cyclecytosolkeratin filamentcolorectal carcinomaadenomadiabetes mellitusneoplasm
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

keratin associated protein 4-5

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜6
colorectal carcinomaOpen Targets
0.01Suggestive
adenomaOpen Targets
0.00Suggestive
diabetes mellitusOpen Targets
0.00Suggestive
hypopharyngeal carcinomaOpen Targets
0.00Suggestive
neoplasmOpen Targets
0.00Suggestive
psoriasisOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
LOC100996750Shared pathway100%KRTAP4-9Shared pathway100%KRTAP4-16Shared pathway100%KRTAP4-3Protein interaction100%KRTAP4-12Protein interaction91%KRTAP4-2Protein interaction90%
Tissue Expression6 tissues
Bone Marrow
0%
Ovary
0%
Heart
0%
Liver
0%
Brain
0%
Lung
0%
Gene Interaction Network
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KRTAP4-5LOC100996750KRTAP4-9KRTAP4-16KRTAP4-3KRTAP4-12KRTAP4-2
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q9BYR2
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.68LoF Tolerant
pLIβ“˜
0.43Tolerant
Observed/Expected LoF0.00 [0.00–1.68]
RankingsWhere KRTAP4-5 stands among ~20K protein-coding genes
  • #17,627of 20,598
    Most Researched8
  • #16,017of 17,882
    Most Constrained (LOEUF)1.68
Genes detectedKRTAP4-5
Sources retrieved0 papers
Response timeβ€”