Based on limited published evidence, LYG2 encodes a potent antibacterial protein involved in innate immunity. UniProt annotations indicate lysozyme activity and role in defense responses to bacteria, particularly Gram-positive bacteria, with localization to the extracellular region. LYG2 possesses protein-binding capacity. In chicken intestinal studies, LYG2 expression in the jejunum correlated significantly with Muricomes bacterial abundance during different egg-laying stages, suggesting potential interaction between host immune gene expression and intestinal microbiota composition 1.