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0 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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MICOS10-NBL1
MICOS10-NBL1 readthrough
Chromosome 1 · 1p36.13
NCBI Gene: 100532736Ensembl: ENSG00000158747.16HGNC: HGNC:7650UniProt: P41271
11PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Tumor Suppressor
DATA QUALITY
✓ Swiss-Prot Reviewed
nontoxic goiterAbnormality of the skeletal systemmultinodular goiterHashimoto's thyroiditis
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

MICOS10-NBL1 readthrough

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsⓘ20
nontoxic goiterOpen Targets
0.45Moderate
Abnormality of the skeletal systemOpen Targets
0.41Moderate
multinodular goiterOpen Targets
0.35Weak
Hashimoto's thyroiditisOpen Targets
0.30Weak
obesityOpen Targets
0.29Weak
hypothyroidismOpen Targets
0.12Weak
obstructive sleep apneaOpen Targets
0.08Suggestive
coronary artery diseaseOpen Targets
0.07Suggestive
bipolar I disorderOpen Targets
0.06Suggestive
cancerOpen Targets
0.05Suggestive
small cell lung carcinomaOpen Targets
0.04Suggestive
neoplasmOpen Targets
0.04Suggestive
aortic diseaseOpen Targets
0.04Suggestive
diabetic nephropathyOpen Targets
0.04Suggestive
ThyrotoxicosisOpen Targets
0.04Suggestive
ovarian cancerOpen Targets
0.03Suggestive
thyroid diseaseOpen Targets
0.03Suggestive
goiterOpen Targets
0.03Suggestive
autoimmune diseaseOpen Targets
0.03Suggestive
infectionOpen Targets
0.03Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
BMP7Protein interaction98%BMP2Protein interaction97%BMP6Protein interaction97%GDF5Protein interaction92%NBL1Protein interaction91%BMP5Protein interaction91%
Tissue Expression6 tissues
Ovary
100%
Heart
27%
Lung
23%
Brain
10%
Bone Marrow
7%
Liver
1%
Gene Interaction Network
Click a node to explore
MICOS10-NBL1BMP7BMP2BMP6GDF5NBL1BMP5
PROTEIN STRUCTURE
Preparing viewer…
PDB4YU8 · 1.80 Å · X-ray
View on RCSB ↗
Constraintⓘ
LOEUFⓘ
0.98LoF Tolerant
pLIⓘ
0.02Tolerant
Observed/Expected LoF0.56 [0.34–0.98]
RankingsWhere MICOS10-NBL1 stands among ~20K protein-coding genes
  • #16,827of 20,598
    Most Researched11
  • #9,335of 17,882
    Most Constrained (LOEUF)0.98
Genes detectedMICOS10-NBL1
Sources retrieved0 papers
Response time—