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GeneE
10 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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NTM
neurotrimin
Chromosome 11 · 11q25
NCBI Gene: 50863Ensembl: ENSG00000182667.15HGNC: HGNC:17941UniProt: B7Z1I4
42PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
protein bindingheterophilic cell-cell adhesionplasma membraneregulation of synapse assemblysmoking initiationAbnormality of the skeletal systemhealth study participationovarian dysfunction
✦AI Summary

Insufficient information available. The provided PubMed abstracts focus exclusively on nontuberculous mycobacteria (NTM) as bacterial pathogens and their clinical management, with no content related to the NTM gene (neurotrimin), a neural cell adhesion molecule. The abstracts do not contain any data on neurotrimin's molecular function, mechanism of action, disease relevance, or clinical significance. To provide an accurate gene function summary grounded in the provided literature, PubMed abstracts specifically investigating neurotrimin's role in neural cell adhesion, synapse assembly, or associated neurological conditions would be required.

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsⓘ20
smoking initiationOpen Targets
0.41Moderate
Abnormality of the skeletal systemOpen Targets
0.40Weak
health study participationOpen Targets
0.39Weak
ovarian dysfunctionOpen Targets
0.35Weak
chronic intestinal vascular insufficiencyOpen Targets
0.35Weak
Abruptio PlacentaeOpen Targets
0.34Weak
HypermetropiaOpen Targets
0.33Weak
uterine polypOpen Targets
0.31Weak
mathematical abilityOpen Targets
0.31Weak
refractive errorOpen Targets
0.30Weak
response to beta blockerOpen Targets
0.29Weak
duodenitisOpen Targets
0.29Weak
idiopathic pulmonary fibrosisOpen Targets
0.29Weak
substance-related disorderOpen Targets
0.29Weak
acute pancreatitisOpen Targets
0.28Weak
renal osteodystrophyOpen Targets
0.28Weak
ovarian neoplasmOpen Targets
0.28Weak
malignant renal pelvis neoplasmOpen Targets
0.28Weak
VitiligoOpen Targets
0.28Weak
stomach diseaseOpen Targets
0.27Weak
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
OPCMLProtein interaction90%HSF4Protein interaction87%IGLON5Shared pathway75%PRNPProtein interaction73%CCDC141Shared pathway40%LSAMPShared pathway40%
Tissue Expression6 tissues
Brain
100%
Heart
25%
Lung
11%
Liver
1%
Ovary
0%
Bone Marrow
0%
Gene Interaction Network
Click a node to explore
NTMOPCMLHSF4IGLON5PRNPCCDC141LSAMP
PROTEIN STRUCTURE
Preparing viewer…
PDB6U7N · 3.32 Å · X-ray
View on RCSB ↗
Constraintⓘ
LOEUFⓘ
0.49Moderately Constrained
pLIⓘ
0.99Intolerant
Observed/Expected LoF0.31 [0.20–0.49]
RankingsWhere NTM stands among ~20K protein-coding genes
  • #9,918of 20,598
    Most Researched42
  • #2,909of 17,882
    Most Constrained (LOEUF)0.49 · top quartile
Genes detectedNTM
Sources retrieved10 papers
Response time—
📄 Sources
10▼
1
Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.
PMID: 32636299
Eur Respir J · 2020
1.00
2
Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.
PMID: 32628747
Clin Infect Dis · 2020
0.90
3
Epidemiology of Mycobacterium abscessus.
PMID: 37778416
Clin Microbiol Infect · 2024
0.80
4
Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.
PMID: 32797222
Clin Infect Dis · 2020
0.70
5
Of tuberculosis and non-tuberculous mycobacterial infections - a comparative analysis of epidemiology, diagnosis and treatment.
PMID: 32552732
J Biomed Sci · 2020
0.60