Based on limited published evidence, PRSS41 (serine protease 41) is a testis-specific serine-type peptidase with predicted roles in protein processing. UniProt annotations indicate localization to intracellular organelles, plasma membrane, and extracellular region. PRSS41 functions as a cancer-testis antigen reactivated in gastric cancer through promoter DNA hypomethylation at CpG site cg08104780, with hypomethylation associated with poor prognosis 1. The gene is not expressed in RBL-2H3 mast cells despite genomic presence 2, suggesting tissue-restricted expression patterns.