HomeAboutRankingsData Sources
Β© 2026 GeneE
🧬
GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
SLC75A1
solute carrier family 75 member 1
Chromosome 4 Β· 4p16.3
NCBI Gene: 10227Ensembl: ENSG00000109736.15HGNC: HGNC:16894UniProt: D6R9N3
28PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transporter
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
sodium-independent organic anion transportprotein bindingcytoplasmic vesicle membranetransmembrane transporter activityAbnormal male internal genitalia morphologymetabolic diseaselower respiratory tract diseasehypertension
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

solute carrier family 75 member 1

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
Abnormal male internal genitalia morphologyOpen Targets
0.12Weak
metabolic diseaseOpen Targets
0.12Weak
lower respiratory tract diseaseOpen Targets
0.11Weak
hypertensionOpen Targets
0.05Suggestive
transient myeloproliferative syndromeOpen Targets
0.05Suggestive
smoking initiationOpen Targets
0.04Suggestive
pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9Open Targets
0.04Suggestive
reticular dysgenesisOpen Targets
0.03Suggestive
chronic obstructive pulmonary diseaseOpen Targets
0.03Suggestive
COVID-19Open Targets
0.03Suggestive
severe acute respiratory syndromeOpen Targets
0.03Suggestive
PainOpen Targets
0.03Suggestive
asthmaOpen Targets
0.03Suggestive
obesityOpen Targets
0.03Suggestive
Nausea and vomitingOpen Targets
0.02Suggestive
Abdominal painOpen Targets
0.02Suggestive
osteoporosis-pseudoglioma syndromeOpen Targets
0.01Suggestive
transitional cell carcinoma of kidneyOpen Targets
0.00Suggestive
hepatocellular carcinomaOpen Targets
0.00Suggestive
chronic kidney diseaseOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
SLCO4C1Shared pathway100%SLCO6A1Shared pathway100%SLCO5A1Shared pathway100%SLCO1B3-SLCO1B7Shared pathway50%SLC22A9Shared pathway50%SLCO2A1Shared pathway33%
Tissue Expression6 tissues
Bone Marrow
100%
Ovary
45%
Lung
44%
Liver
13%
Heart
7%
Brain
6%
Gene Interaction Network
Click a node to explore
SLC75A1SLCO4C1SLCO6A1SLCO5A1SLCO1B3-SLCO1B7SLC22A9SLCO2A1
PROTEIN STRUCTURE
Preparing viewer…
PDB6S4M Β· 2.40 Γ… Β· X-ray
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.60LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF1.28 [1.03–1.60]
RankingsWhere SLC75A1 stands among ~20K protein-coding genes
  • #12,449of 20,598
    Most Researched28
  • #15,676of 17,882
    Most Constrained (LOEUF)1.60
Genes detectedSLC75A1
Sources retrieved0 papers
Response timeβ€”