TNFRSF10B — TNF receptor superfamily member 10b

30 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

414PubMed Papers

#693 · top 4% of 19K genes

21Diseases

top 8%

7Drugs

top 24%

2Pathogenic Variants

top 76%

Clinical TrialsOMIM Disease GeneReceptorHighly StudiedExperimental GO EvidenceSwiss-Prot Reviewed

plasma membranecell surfaceTRAIL receptor activitydefense response to tumor cellbasal cell carcinomahead and neck squamous cell carcinomaAbnormality of the skeletal systemIron deficiency anemia

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

TNF receptor superfamily member 10b

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations21

basal cell carcinomaOpen Targets

0.47Moderate

head and neck squamous cell carcinomaOpen Targets

0.45Moderate

Abnormality of the skeletal systemOpen Targets

0.41Moderate

Iron deficiency anemiaOpen Targets

0.39Weak

renal carcinomaOpen Targets

0.36Weak

clear cell renal carcinomaOpen Targets

0.36Weak

intestinal diseaseOpen Targets

0.29Weak

vascular diseaseOpen Targets

0.29Weak

prostate carcinomaOpen Targets

0.28Weak

non-melanoma skin carcinomaOpen Targets

0.24Weak

skin cancerOpen Targets

0.22Weak

jaw diseaseOpen Targets

0.21Weak

placenta praeviaOpen Targets

0.20Weak

bipolar disorderOpen Targets

0.18Weak

ovarian dysfunctionOpen Targets

0.15Weak

cancerOpen Targets

0.12Weak

neoplasmOpen Targets

0.12Weak

non-small cell lung carcinomaOpen Targets

0.11Weak

melanomaOpen Targets

0.10Weak

ovarian cancerOpen Targets

0.10Weak

Squamous cell carcinoma of the head and neckUniProt

Pathogenic Variants2

NM_003842.5(TNFRSF10B):c.598del (p.Ser200fs)Likely pathogenic

Squamous cell carcinoma of the head and neck

★☆☆☆2024→ Residue 200

NM_003842.5(TNFRSF10B):c.1150_1151dup (p.Met385fs)Pathogenic

Squamous cell carcinoma of the head and neck

☆☆☆☆1998→ Residue 385

Drug Targets07

APOMABIND