25 sources retrieved · Most recent: April 2026 · Index updated 16 days ago
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414PubMed Papers
21Diseases
7Drugs
2Pathogenic Variants
RESEARCH IMPACTHighly Studied
CLINICALClinical TrialsOMIM Disease Gene
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
plasma membranecell surfaceTRAIL receptor activitydefense response to tumor cellbasal cell carcinomahead and neck squamous cell carcinomaAbnormality of the skeletal systemIron deficiency anemia
AI summary not yet available. Showing NCBI Gene summary.
TNF receptor superfamily member 10b
⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
basal cell carcinomaOpen Targets
head and neck squamous cell carcinomaOpen Targets
Abnormality of the skeletal systemOpen Targets
Iron deficiency anemiaOpen Targets
renal carcinomaOpen Targets
clear cell renal carcinomaOpen Targets
intestinal diseaseOpen Targets
vascular diseaseOpen Targets
prostate carcinomaOpen Targets
non-melanoma skin carcinomaOpen Targets
placenta praeviaOpen Targets
bipolar disorderOpen Targets
ovarian dysfunctionOpen Targets
non-small cell lung carcinomaOpen Targets
ovarian cancerOpen Targets
Squamous cell carcinoma of the head and neckUniProt
NM_003842.5(TNFRSF10B):c.598del (p.Ser200fs)Likely pathogenic
Squamous cell carcinoma of the head and neck
★☆☆☆2024→ Residue 200
NM_003842.5(TNFRSF10B):c.1150_1151dup (p.Met385fs)Pathogenic
Squamous cell carcinoma of the head and neck
☆☆☆☆1998→ Residue 385
APOMABIND
Tumor necrosis factor receptor superfamily member 10B agonist
CONATUMUMABPhase II
Tumor necrosis factor receptor superfamily member 10B agonist
colorectal cancer
DROZITUMABPhase II
Tumor necrosis factor receptor superfamily member 10B agonist
non-Hodgkins lymphoma
DULANERMINPhase I/II
TRAIL receptor-1 agonist
non-Hodgkins lymphoma
LBY-135Phase I
Tumor necrosis factor receptor superfamily member 10B agonist
LEXATUMUMABPhase II
Tumor necrosis factor receptor superfamily member 10B agonist
TIGATUZUMABPhase II
Tumor necrosis factor receptor superfamily member 10B agonist
breast cancer