ATP5MG — ATP synthase membrane subunit g

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

93PubMed Papers

#5,142 · top 26% of 19K genes

20Diseases

top 40%

0Drugs

0Pathogenic Variants

TransporterExperimental GO EvidenceSwiss-Prot Reviewed

proton-transporting ATP synthase activity, rotational mechanismproton-transporting ATP synthase complexprotein bindingmitochondrionenteritisautoimmune diseasearthritisrheumatoid arthritis

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

ATP synthase membrane subunit g

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations20

enteritisOpen Targets

0.16Weak

autoimmune diseaseOpen Targets

0.15Weak

arthritisOpen Targets

0.13Weak

rheumatoid arthritisOpen Targets

0.10Weak

major depressive disorderOpen Targets

0.08Suggestive

Hemolytic anemia due to red cell pyruvate kinase deficiencyOpen Targets

0.05Suggestive

hemoglobin D diseaseOpen Targets

0.05Suggestive

dehydrated hereditary stomatocytosisOpen Targets

0.05Suggestive

dominant beta-thalassemiaOpen Targets

0.04Suggestive

Hyperlipoproteinemia type 1Open Targets

0.04Suggestive

Hemoglobin E - beta-thalassemiaOpen Targets

0.04Suggestive

hemoglobin E-beta-thalassemia syndromeOpen Targets

0.04Suggestive

hemoglobin H diseaseOpen Targets

0.04Suggestive

Congenital dyserythropoietic anemia type IOpen Targets

0.04Suggestive

Blackfan-Diamond anemiaOpen Targets

0.04Suggestive

hemoglobin E diseaseOpen Targets

0.04Suggestive

Adult-onset autosomal recessive sideroblastic anemiaOpen Targets

0.04Suggestive

sideroblastic anemia 3Open Targets

0.04Suggestive

Hemoglobin C - beta-thalassemiaOpen Targets

0.04Suggestive

hemoglobin C-beta-thalassemia syndromeOpen Targets

0.04Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Heart

100%

Brain

94%

Liver

64%

Ovary

50%

Lung

48%

Bone Marrow

29%

Gene Interaction Network6 neighbors

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Structure10 PDB hits

Preparing viewer…

PDB8H9S · 2.53 Å · EM

View on RCSB

ConstraintgnomAD v4.1

LOEUFⓘ

1.12LoF Tolerant

pLIⓘ

0.03Tolerant

Observed/Expected LoF0.60 [0.34–1.12]

Rankings2 dim

Where ATP5MG stands among ~20K protein-coding genes

#5,124of 20,598
Most Researched93 · top quartile
#11,600of 17,882
Most Constrained (LOEUF)1.12