Based on limited published evidence, DEFB110 encodes defensin beta 110, a peptide with antimicrobial activity. UniProt annotations indicate antibacterial defense response function. The protein contains CCR6 chemokine receptor binding capacity and exhibits chemoattractant activity, suggesting immune cell recruitment roles. A putative hBD10 peptide derived from DEFB110 demonstrated antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Mycobacterium tuberculosis without hemolytic effects 1, supporting its potential as an antimicrobial agent against multidrug-resistant bacteria.