0 sources retrieved · Most recent: April 2026 · Index updated 15 days ago
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3PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
endoplasmic reticulum membranefusion of sperm to egg plasma membrane involved in single fertilizationsperm-egg recognitionmaintenance of protein localization in endoplasmic reticulumSAPHO syndromeazoospermiaMale infertility with spermatogenesis disorder due to single gene mutationRare genetic female infertility
AI summary not yet available. Showing NCBI Gene summary.
Frey regulator of sperm-oocyte fusion 1
⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
SAPHO syndromeOpen Targets
Male infertility with spermatogenesis disorder due to single gene mutationOpen Targets
Rare genetic female infertilityOpen Targets
Female infertility due to fertilization defectOpen Targets
spermatogenic failure 3Open Targets
spermatogenic failure 55Open Targets
partial chromosome Y deletionOpen Targets
spermatogenic failure 61Open Targets
spermatogenic failure 62Open Targets
spermatogenic failure 88Open Targets
spermatogenic failure 59Open Targets
spermatogenic failure 60Open Targets
spermatogenic failure 73Open Targets
spermatogenic failure 74Open Targets
spermatogenic failure 16Open Targets
spermatogenic failure 21Open Targets
oocyte maturation defect 14Open Targets
oocyte maturation defect 5Open Targets
spermatogenic failure 87Open Targets
No pathogenic variants reported on ClinVar for this gene.