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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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GGTLC3
gamma-glutamyltransferase light chain family member 3
Chromosome 22 Β· 22q11.21
NCBI Gene: 728226Ensembl: ENSG00000274252.2HGNC: HGNC:33426UniProt: B5MD39
5PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
extracellular exosomeleukotriene D4 biosynthetic processglutathione gamma-glutamate hydrolaseglutathione catabolic processmetabolic syndromenon-alcoholic fatty liver diseasehepatocellular carcinomadiabetes mellitus
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

gamma-glutamyltransferase light chain family member 3

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
metabolic syndromeOpen Targets
0.12Weak
non-alcoholic fatty liver diseaseOpen Targets
0.12Weak
hepatocellular carcinomaOpen Targets
0.12Weak
diabetes mellitusOpen Targets
0.12Weak
neoplasmOpen Targets
0.12Weak
type 2 diabetes mellitusOpen Targets
0.12Weak
strokeOpen Targets
0.11Weak
hypertensionOpen Targets
0.11Weak
chronic kidney diseaseOpen Targets
0.11Weak
cancerOpen Targets
0.11Weak
cardiovascular diseaseOpen Targets
0.10Weak
gestational diabetesOpen Targets
0.10Weak
breast cancerOpen Targets
0.10Suggestive
myeloid sarcomaOpen Targets
0.10Suggestive
fatty liver diseaseOpen Targets
0.10Suggestive
lung cancerOpen Targets
0.09Suggestive
atrial fibrillationOpen Targets
0.09Suggestive
dementiaOpen Targets
0.09Suggestive
Ischemic strokeOpen Targets
0.09Suggestive
cervical cancerOpen Targets
0.09Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
GGTLC2Shared pathway100%GGTLC1Shared pathway100%AGAProtein interaction80%GGCTProtein interaction80%GGT6Protein interaction59%GGTA1Shared pathway50%
Tissue Expression6 tissues
Lung
100%
Heart
0%
Brain
0%
Bone Marrow
0%
Ovary
0%
Liver
0%
Gene Interaction Network
Click a node to explore
GGTLC3GGTLC2GGTLC1AGAGGCTGGT6GGTA1
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt B5MD39
View on AlphaFold β†—
RankingsWhere GGTLC3 stands among ~20K protein-coding genes
  • #18,333of 20,598
    Most Researched5
Genes detectedGGTLC3
Sources retrieved0 papers
Response timeβ€”