1 sources retrieved · Most recent: April 2026 · Index updated 15 days ago
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4PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Swiss-Prot Reviewed
neurodegenerative diseaseFuchs endothelial corneal dystrophyearly-onset non-syndromic cataractOkt4 epitope deficiency
Based on limited published evidence, GIMAP1-GIMAP5 readthrough is a transcribed region on chromosome 7 with unknown characterized molecular function. Recent RNA sequencing studies identified GIMAP1-GIMAP5 as significantly downregulated in lung adenocarcinoma tissues compared to benign lung tissues 1. Expression levels of GIMAP1-GIMAP5 demonstrated strong correlation with prognosis in lung adenocarcinoma patients and contributed to a predictive nomogram model for distinguishing malignant from benign pulmonary ground-glass nodules 1. No other functional characterization is currently available in the literature.
1
GIMAP1-GIMAP5 is downregulated in lung adenocarcinoma compared to benign nodules; expression levels correlate with patient prognosis and serve as a biomarker in predictive nomogram models
PMID: 40535419⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
neurodegenerative diseaseOpen Targets
Fuchs endothelial corneal dystrophyOpen Targets
early-onset non-syndromic cataractOpen Targets
Okt4 epitope deficiencyOpen Targets
Lisch epithelial corneal dystrophyOpen Targets
X-linked endothelial corneal dystrophyOpen Targets
X-linked corneal dermoidOpen Targets
posterior polymorphous corneal dystrophyOpen Targets
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positiveOpen Targets
T-B+ severe combined immunodeficiency due to JAK3 deficiencyOpen Targets
isolated agammaglobulinemiaOpen Targets
Familial hemophagocytic lymphohistiocytosisOpen Targets
autosomal dominant keratitisOpen Targets
congenital hereditary endothelial dystrophy of corneaOpen Targets
lattice corneal dystrophy type IOpen Targets
Central cloudy dystrophy of FrancoisOpen Targets
central cloudy dystrophy of FrançoisOpen Targets
Schnyder corneal dystrophyOpen Targets
combined immunodeficiency due to ZAP70 deficiencyOpen Targets
granular corneal dystrophy type IOpen Targets
No pathogenic variants reported on ClinVar for this gene.
No tissue expression data available for this gene.