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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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IFT70B
intraflagellar transport 70B
Chromosome 2 Β· 2q31.2
NCBI Gene: 150737Ensembl: ENSG00000196659.10HGNC: HGNC:26425UniProt: Q8N4P2
17PubMed Papers
13Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
intraciliary transport particle Aprotein bindingintraciliary transportaxonemal microtubulesynpolydactylyliver diseaseAbnormality of the skeletal systemneuronal ceroid lipofuscinosis 1
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

intraflagellar transport 70B

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜13
synpolydactylyOpen Targets
0.12Weak
liver diseaseOpen Targets
0.04Suggestive
Abnormality of the skeletal systemOpen Targets
0.04Suggestive
neuronal ceroid lipofuscinosis 1Open Targets
0.04Suggestive
familial isolated congenital aspleniaOpen Targets
0.04Suggestive
diabetes mellitusOpen Targets
0.04Suggestive
cervical carcinomaOpen Targets
0.03Suggestive
obstructive sleep apneaOpen Targets
0.03Suggestive
ependymomaOpen Targets
0.02Suggestive
insomniaOpen Targets
0.02Suggestive
childhood supratentorial ependymomaOpen Targets
0.02Suggestive
Platelet storage pool diseaseOpen Targets
0.01Suggestive
ciliopathyOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
IFT52Protein interaction100%IFT20Protein interaction99%IFT46Protein interaction91%IFT74Protein interaction91%IFT80Protein interaction87%IFT172Protein interaction84%
Tissue Expression6 tissues
Brain
100%
Bone Marrow
45%
Heart
38%
Liver
27%
Ovary
25%
Lung
22%
Gene Interaction Network
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IFT70BIFT52IFT20IFT46IFT74IFT80IFT172
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q8N4P2
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
0.95LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.70 [0.53–0.95]
RankingsWhere IFT70B stands among ~20K protein-coding genes
  • #15,022of 20,598
    Most Researched17
  • #8,837of 17,882
    Most Constrained (LOEUF)0.95
Genes detectedIFT70B
Sources retrieved0 papers
Response timeβ€”