KPLCE — KPRP N-terminal and LCE C-terminal like protein

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

46PubMed Papers

#9,404 · top 48% of 19K genes

17Diseases

top 91%

0Drugs

0Pathogenic Variants

Swiss-Prot Reviewed

epidermis developmentatopic eczemapsoriasisrosaceasquamous cell lung carcinoma

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

KPRP N-terminal and LCE C-terminal like protein

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations17

atopic eczemaOpen Targets

0.03Suggestive

psoriasisOpen Targets

0.01Suggestive

rosaceaOpen Targets

0.01Suggestive

lung adenocarcinomaOpen Targets

0.01Suggestive

squamous cell lung carcinomaOpen Targets

0.01Suggestive

gastric carcinomaOpen Targets

0.01Suggestive

skin diseaseOpen Targets

0.00Suggestive

cutaneous lupus erythematosusOpen Targets

0.00Suggestive

periodontal disorderOpen Targets

0.00Suggestive

pneumoniaOpen Targets

0.00Suggestive

popliteal pterygium syndromeOpen Targets

0.00Suggestive

breast cancerOpen Targets

0.00Suggestive

rheumatoid arthritisOpen Targets

0.00Suggestive

CandidemiaOpen Targets

0.00Suggestive

infectious diseaseOpen Targets

0.00Suggestive

lung cancerOpen Targets

0.00Suggestive

tuberculosisOpen Targets

0.00Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Lung

100%

Liver

100%

Ovary

75%

Heart

Bone Marrow

Brain

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt Q5T750

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ConstraintgnomAD v4.1

LOEUFⓘ

1.72LoF Tolerant

pLIⓘ

0.01Tolerant

Observed/Expected LoF0.93 [0.51–1.72]

Rankings2 dim

Where KPLCE stands among ~20K protein-coding genes

#9,339of 20,598
Most Researched46
#16,190of 17,882
Most Constrained (LOEUF)1.72