Based on limited published evidence, LRRC40 is a membrane-associated protein involved in protein binding and intracellular signal transduction. LRRC40 was identified as a component of an LRIG1 protein interaction network that regulates growth factor receptor signaling 1. Additionally, LRRC40 has been identified as a candidate gene in autism spectrum disorder, where it interacts with PlxnA2 in a neural pathway; pathogenic variants in LRRC40 result in reduced protein levels 2. The precise molecular function of LRRC40 remains largely unknown.