LTAP1 — lipid transport auxiliary protein 1

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

39PubMed Papers

#10,337 · top 53% of 19K genes

20Diseases

top 58%

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

Golgi apparatusmitochondrionphagocytosisendoplasmic reticulum-plasma membrane contact siteprostate carcinomalung adenocarcinomaasthmairritable bowel syndrome

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

lipid transport auxiliary protein 1

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations20

prostate carcinomaOpen Targets

0.08Suggestive

lung adenocarcinomaOpen Targets

0.07Suggestive

asthmaOpen Targets

0.05Suggestive

irritable bowel syndromeOpen Targets

0.05Suggestive

Combined hyperlipidemiaOpen Targets

0.04Suggestive

hypertriglyceridemia 2Open Targets

0.04Suggestive

pancreatic triacylglycerol lipase deficiencyOpen Targets

0.04Suggestive

chylomicron retention diseaseOpen Targets

0.04Suggestive

sitosterolemia 2Open Targets

0.03Suggestive

thyroid hormone metabolism, abnormal, 2Open Targets

0.03Suggestive

familial hypercholesterolemiaOpen Targets

0.03Suggestive

homozygous familial hypercholesterolemiaOpen Targets

0.03Suggestive

smoking initiationOpen Targets

0.03Suggestive

Congenital chronic diarrhea with protein-losing enteropathyOpen Targets

0.03Suggestive

congenital diarrhea 7 with exudative enteropathyOpen Targets

0.03Suggestive

DiarrheaOpen Targets

0.03Suggestive

congenital lethal erythrodermaOpen Targets

0.03Suggestive

familial apolipoprotein C-II deficiencyOpen Targets

0.03Suggestive

Hyperlipoproteinemia type 1Open Targets

0.03Suggestive

nephrotic syndrome, type 2Open Targets

0.03Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Heart

100%

Brain

91%

Liver

78%

Lung

61%

Ovary

35%

Bone Marrow

32%

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt Q09GN0

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ConstraintgnomAD v4.1

LOEUFⓘ

0.95LoF Tolerant

pLIⓘ

0.00Tolerant

Observed/Expected LoF0.63 [0.43–0.95]

Rankings2 dim

Where LTAP1 stands among ~20K protein-coding genes

#10,351of 20,598
Most Researched39
#8,865of 17,882
Most Constrained (LOEUF)0.95