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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
LTAP1
lipid transport auxiliary protein 1
Chromosome 1 Β· 1q21.3
NCBI Gene: 25912Ensembl: ENSG00000143612.21HGNC: HGNC:29876UniProt: Q09GN0
39PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
Golgi apparatusmitochondrionphagocytosisendoplasmic reticulum-plasma membrane contact siteprostate carcinomalung adenocarcinomaasthmairritable bowel syndrome
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

lipid transport auxiliary protein 1

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
prostate carcinomaOpen Targets
0.08Suggestive
lung adenocarcinomaOpen Targets
0.07Suggestive
asthmaOpen Targets
0.05Suggestive
irritable bowel syndromeOpen Targets
0.05Suggestive
Combined hyperlipidemiaOpen Targets
0.04Suggestive
hypertriglyceridemia 2Open Targets
0.04Suggestive
pancreatic triacylglycerol lipase deficiencyOpen Targets
0.04Suggestive
chylomicron retention diseaseOpen Targets
0.04Suggestive
sitosterolemia 2Open Targets
0.03Suggestive
thyroid hormone metabolism, abnormal, 2Open Targets
0.03Suggestive
familial hypercholesterolemiaOpen Targets
0.03Suggestive
homozygous familial hypercholesterolemiaOpen Targets
0.03Suggestive
smoking initiationOpen Targets
0.03Suggestive
Congenital chronic diarrhea with protein-losing enteropathyOpen Targets
0.03Suggestive
congenital diarrhea 7 with exudative enteropathyOpen Targets
0.03Suggestive
DiarrheaOpen Targets
0.03Suggestive
congenital lethal erythrodermaOpen Targets
0.03Suggestive
familial apolipoprotein C-II deficiencyOpen Targets
0.03Suggestive
Hyperlipoproteinemia type 1Open Targets
0.03Suggestive
nephrotic syndrome, type 2Open Targets
0.03Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
CD302Shared pathway100%ANXA11Shared pathway50%CEACAM4Shared pathway50%PLD4Shared pathway50%TAFA4Shared pathway33%NCF4Shared pathway33%
Tissue Expression6 tissues
Heart
100%
Brain
91%
Liver
78%
Lung
61%
Ovary
35%
Bone Marrow
32%
Gene Interaction Network
Click a node to explore
LTAP1CD302ANXA11CEACAM4PLD4TAFA4NCF4
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q09GN0
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
0.95LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.63 [0.43–0.95]
RankingsWhere LTAP1 stands among ~20K protein-coding genes
  • #10,351of 20,598
    Most Researched39
  • #8,865of 17,882
    Most Constrained (LOEUF)0.95
Genes detectedLTAP1
Sources retrieved0 papers
Response timeβ€”