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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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MBD3L3
methyl-CpG binding domain protein 3 like 3
Chromosome 19 Β· 19p13.2
NCBI Gene: 653657Ensembl: ENSG00000182315.10HGNC: HGNC:37205UniProt: A6NE82
3PubMed Papers
12Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transcription Factor
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingmethyl-CpG bindingnegative regulation of transcription by RNA polymerase IIDNA methylation-dependent constitutive heterochromatin formationtype 2 diabetes mellitusAbnormality of the skeletal systemclear cell renal carcinomadiabetes mellitus
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

methyl-CpG binding domain protein 3 like 3

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜12
type 2 diabetes mellitusOpen Targets
0.05Suggestive
Abnormality of the skeletal systemOpen Targets
0.05Suggestive
clear cell renal carcinomaOpen Targets
0.04Suggestive
diabetes mellitusOpen Targets
0.04Suggestive
renal carcinomaOpen Targets
0.03Suggestive
polycystic ovary syndromeOpen Targets
0.03Suggestive
goutOpen Targets
0.03Suggestive
cervical carcinomaOpen Targets
0.03Suggestive
preeclampsiaOpen Targets
0.02Suggestive
dementiaOpen Targets
0.02Suggestive
ovarian neoplasmOpen Targets
0.02Suggestive
cancerOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
ATF7IPShared pathway100%MBD3L1Shared pathway100%MBD3L4Shared pathway100%MBD3L2BShared pathway100%MBD3L5Protein interaction86%MBD3L2Protein interaction73%
Tissue Expression6 tissues
Lung
0%
Bone Marrow
0%
Heart
0%
Ovary
0%
Liver
0%
Brain
0%
Gene Interaction Network
Click a node to explore
MBD3L3ATF7IPMBD3L1MBD3L4MBD3L2BMBD3L5MBD3L2
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt A6NE82
View on AlphaFold β†—
RankingsWhere MBD3L3 stands among ~20K protein-coding genes
  • #18,904of 20,598
    Most Researched3
Genes detectedMBD3L3
Sources retrieved0 papers
Response timeβ€”