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0 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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MMGT1
membrane magnesium transporter 1
Chromosome X · Xq26.3
NCBI Gene: 93380Ensembl: ENSG00000169446.7HGNC: HGNC:28100UniProt: Q8N4V1
76PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transporter
DATA QUALITY
✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
membraneprotein insertion into ER membrane by stop-transfer membrane-anchor sequenceEMC complexendoplasmic reticulum membranedevelopmental disorder of mental healthHypotoniaComplete right bundle branch blockMyocardial Ischemia
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

membrane magnesium transporter 1

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsⓘ20
developmental disorder of mental healthOpen Targets
0.23Weak
HypotoniaOpen Targets
0.12Weak
Complete right bundle branch blockOpen Targets
0.02Suggestive
Myocardial IschemiaOpen Targets
0.02Suggestive
coronary artery diseaseOpen Targets
0.02Suggestive
coronary atherosclerosisOpen Targets
0.02Suggestive
percutaneous transluminal coronary angioplastyOpen Targets
0.02Suggestive
coronary artery bypassOpen Targets
0.02Suggestive
infectionOpen Targets
0.00Suggestive
Alzheimer diseaseOpen Targets
0.00Suggestive
retinal degenerationOpen Targets
0.00Suggestive
candidiasisOpen Targets
0.00Suggestive
asthmaOpen Targets
0.00Suggestive
atopic eczemaOpen Targets
0.00Suggestive
viral diseaseOpen Targets
0.00Suggestive
acute myeloid leukemiaOpen Targets
0.00Suggestive
melanomaOpen Targets
0.00Suggestive
sarcomaOpen Targets
0.00Suggestive
thyroid cancer, nonmedullary, 1Open Targets
0.00Suggestive
uterine corpus endometrial carcinomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
EMC10Protein interaction100%EMC2Protein interaction75%EMC8Protein interaction75%EMC1Protein interaction75%EMC9Protein interaction75%EMC4Protein interaction75%
Tissue Expression6 tissues
Brain
100%
Bone Marrow
74%
Heart
70%
Lung
53%
Ovary
37%
Liver
19%
Gene Interaction Network
Click a node to explore
MMGT1EMC10EMC2EMC8EMC1EMC9EMC4
PROTEIN STRUCTURE
Preparing viewer…
PDB8J0O · 3.32 Å · EM
View on RCSB ↗
Constraintⓘ
LOEUFⓘ
0.54Moderately Constrained
pLIⓘ
0.94Intolerant
Observed/Expected LoF0.17 [0.07–0.54]
RankingsWhere MMGT1 stands among ~20K protein-coding genes
  • #6,261of 20,598
    Most Researched76
  • #3,418of 17,882
    Most Constrained (LOEUF)0.54 · top quartile
Genes detectedMMGT1
Sources retrieved0 papers
Response time—