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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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MROH2B
maestro heat like repeat family member 2B
Chromosome 5 Β· 5p13.1
NCBI Gene: 133558Ensembl: ENSG00000171495.17HGNC: HGNC:26857UniProt: B3KXY2
13PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
sperm flagellumsperm midpieceacrosomal vesiclecytoplasmProptosisplacenta praeviaalcohol drinkingovarian dysfunction
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

maestro heat like repeat family member 2B

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
ProptosisOpen Targets
0.27Weak
placenta praeviaOpen Targets
0.26Weak
alcohol drinkingOpen Targets
0.24Weak
ovarian dysfunctionOpen Targets
0.23Weak
rectosigmoid junction neoplasmOpen Targets
0.07Suggestive
Duchenne muscular dystrophyOpen Targets
0.04Suggestive
experimental autoimmune encephalomyelitisOpen Targets
0.04Suggestive
benign neoplasm of adrenal glandOpen Targets
0.02Suggestive
Benign Brain NeoplasmOpen Targets
0.02Suggestive
Central Nervous System NeoplasmOpen Targets
0.02Suggestive
male reproductive organ cancerOpen Targets
0.02Suggestive
response to xenobiotic stimulusOpen Targets
0.02Suggestive
pulmonary tuberculosisOpen Targets
0.02Suggestive
myeloid sarcomaOpen Targets
0.01Suggestive
Autoimmune HepatitisOpen Targets
0.01Suggestive
cancerOpen Targets
0.01Suggestive
endometriosisOpen Targets
0.01Suggestive
multiple system atrophyOpen Targets
0.01Suggestive
Posterior Leukoencephalopathy SyndromeOpen Targets
0.01Suggestive
Dravet syndromeOpen Targets
0.01Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
CREMShared pathway100%TCP11Shared pathway33%SRCAPShared pathway33%ATF1Shared pathway17%AKAP12Shared pathway11%GHRHRShared pathway9%
Tissue Expression6 tissues
Ovary
100%
Liver
86%
Lung
17%
Bone Marrow
3%
Brain
0%
Heart
0%
Gene Interaction Network
Click a node to explore
MROH2BCREMTCP11SRCAPATF1AKAP12GHRHR
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q4G0Z6
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.02LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.89 [0.78–1.02]
RankingsWhere MROH2B stands among ~20K protein-coding genes
  • #16,227of 20,598
    Most Researched13
  • #10,015of 17,882
    Most Constrained (LOEUF)1.02
Genes detectedMROH2B
Sources retrieved0 papers
Response timeβ€”