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0 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
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MRPL57
mitochondrial ribosomal protein L57
Chromosome 13 Β· 13q12.11
NCBI Gene: 78988Ensembl: ENSG00000173141.6HGNC: HGNC:14514UniProt: Q9BQC6
39PubMed Papers
4Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Hub Gene
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingmitochondrionmitochondrial large ribosomal subunitmitochondrial ribosomehepatocellular carcinomaspinal cord injurycolorectal carcinomapancreatic ductal adenocarcinoma
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

mitochondrial ribosomal protein L57

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜4
hepatocellular carcinomaOpen Targets
0.15Weak
spinal cord injuryOpen Targets
0.05Suggestive
colorectal carcinomaOpen Targets
0.00Suggestive
pancreatic ductal adenocarcinomaOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
GATBShared pathway100%MRPS31Shared pathway100%MRPS28Shared pathway100%PTCD3Shared pathway100%MRPS10Shared pathway100%MRPS22Shared pathway100%
Tissue Expression6 tissues
Liver
100%
Ovary
61%
Heart
58%
Brain
56%
Lung
51%
Bone Marrow
41%
Gene Interaction Network
Click a node to explore
MRPL57GATBMRPS31MRPS28PTCD3MRPS10MRPS22
PROTEIN STRUCTURE
Preparing viewer…
PDB7OF0 Β· 2.20 Γ… Β· EM
View on RCSB β†—
Constraintβ“˜
LOEUFβ“˜
1.92LoF Tolerant
pLIβ“˜
0.06Tolerant
Observed/Expected LoF1.32 [0.43–1.92]
RankingsWhere MRPL57 stands among ~20K protein-coding genes
  • #10,358of 20,598
    Most Researched39
  • #17,360of 17,882
    Most Constrained (LOEUF)1.92
Genes detectedMRPL57
Sources retrieved0 papers
Response timeβ€”