1 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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6PubMed Papers
5Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
plasma membraneolfactory receptor activitysystem processG protein-coupled receptor signaling pathwayalcohol drinkingprostate carcinomaAlzheimer diseaseneoplasm
OR51G1 is an olfactory receptor with odorant receptor activity localized to the plasma membrane. Based on limited published evidence, a rare missense variant (rs146006146, p.R272H) in OR51G1 was identified as a candidate genetic risk factor associated with Alzheimer's disease in a whole-genome sequencing study of Japanese populations 1. However, functional characterization of this OR51G1 variant has not been reported, and its contribution to disease pathogenesis remains unclear.
1
Identified OR51G1 missense variant (rs146006146, p.R272H) as a rare variant candidate associated with Alzheimer's disease through whole-genome sequencing
PMID: 35264725⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
alcohol drinkingOpen Targets
prostate carcinomaOpen Targets
Alzheimer diseaseOpen Targets
Mental deteriorationOpen Targets
No pathogenic variants reported on ClinVar for this gene.
No tissue expression data available for this gene.