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GeneE
1 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
OR51T1
olfactory receptor family 51 subfamily T member 1
Chromosome 11 Β· 11p15.4
NCBI Gene: 401665Ensembl: ENSG00000176900.2HGNC: HGNC:15205UniProt: A0A0C4DFX5
2PubMed Papers
3Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Receptor
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
plasma membraneolfactory receptor activitysystem processG protein-coupled receptor signaling pathwayalcohol drinkingneoplasmposterior cortical atrophy
✦AI Summary

OR51T1 is an olfactory receptor gene located on chromosome 11. Based on limited published evidence, OR51T1 encodes an odorant receptor protein with olfactory receptor activity localized to the plasma membrane. The gene belongs to olfactory receptor family 51 subfamily T and clusters with other known human OR genes based on sequence similarity 1. Specific ligand specificity and detailed molecular mechanisms remain to be characterized.

Sources cited
1
OR51T1 identified as a known human olfactory receptor gene clustering with giant panda OR genes based on sequence similarity analysis
PMID: 36978520
⚠Limited data available β€” This gene has 1 indexed publication. Summary and analysis may be incomplete.
Disease Associationsβ“˜3
alcohol drinkingOpen Targets
0.02Suggestive
neoplasmOpen Targets
0.00Suggestive
posterior cortical atrophyOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
OR51G1Shared pathway100%OR51B2Shared pathway100%OR51L1Shared pathway100%OR51A7Shared pathway100%OR51F2Shared pathway100%OR56A4Shared pathway100%
Tissue Expression6 tissues
Lung
0%
Bone Marrow
0%
Ovary
0%
Heart
0%
Liver
0%
Brain
0%
Gene Interaction Network
Click a node to explore
OR51T1OR51G1OR51B2OR51L1OR51A7OR51F2OR56A4
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q8NGJ9
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.94LoF Tolerant
pLIβ“˜
0.05Tolerant
Observed/Expected LoF1.92 [0.51–1.94]
RankingsWhere OR51T1 stands among ~20K protein-coding genes
  • #19,189of 20,598
    Most Researched2
  • #17,564of 17,882
    Most Constrained (LOEUF)1.94
Genes detectedOR51T1
Sources retrieved1 papers
Response timeβ€”
πŸ“„ Sources
1
1
Comparative Analysis of Olfactory Receptor Repertoires Sheds Light on the Diet Adaptation of the Bamboo-Eating Giant Panda Based on the Chromosome-Level Genome.
PMID: 36978520
Animals (Basel) Β· 2023
1.00