Based on limited published evidence, PACRGL is a parkin coregulated-like protein with demonstrated protein binding capacity. PACRGL belongs to the PACRG family of proteins, which function in axoneme formation. The homologous PACRG protein binds at the inner junction between doublet microtubules and mediates dual tubulin interactions to catalyze inner junction formation during axoneme assembly 1. PACRGL likely shares similar roles in regulating axonemal structure, though its specific molecular interactions require further characterization.