PRAMEF9 — PRAME family member 9

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

7PubMed Papers

#17,913 · top 92% of 19K genes

0Diseases

0Drugs

0Pathogenic Variants

Experimental GO EvidenceSwiss-Prot Reviewed

Cul2-RING ubiquitin ligase complexproteasome-mediated ubiquitin-dependent protein catabolic processubiquitin-like ligase-substrate adaptor activitynegative regulation of apoptotic process

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

PRAME family member 9

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression

No tissue expression data available for this gene.

Gene Interaction Network6 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt A0A096LNW4

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ConstraintgnomAD v4.1

LOEUFⓘ

1.24LoF Tolerant

pLIⓘ

0.46Tolerant

Observed/Expected LoF0.27 [0.09–1.24]

Rankings2 dim

Where PRAMEF9 stands among ~20K protein-coding genes

#17,929of 20,598
Most Researched7
#13,130of 17,882
Most Constrained (LOEUF)1.24