HomeAboutRankingsData Sources
Β© 2026 GeneE
🧬
GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
PRAMEF27
PRAME family member 27
Chromosome 1 Β· 1p36.21
NCBI Gene: 101929983Ensembl: ENSG00000274764.6HGNC: HGNC:51234UniProt: A3QJZ7
2PubMed Papers
0Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
ubiquitin-like ligase-substrate adaptor activityproteasome-mediated ubiquitin-dependent protein catabolic processcytoplasmCul2-RING ubiquitin ligase complex
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

PRAME family member 27

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
PRAMEF1Shared pathway100%PRAMEF2Shared pathway100%PRAMEF5Shared pathway100%PRAMEF9Shared pathway100%PRAMEF10Shared pathway100%PRAMEF12Shared pathway100%
Tissue Expression

No tissue expression data available for this gene.

Gene Interaction Network
Click a node to explore
PRAMEF27PRAMEF1PRAMEF2PRAMEF5PRAMEF9PRAMEF10PRAMEF12
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt A3QJZ7
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
0.94LoF Tolerant
pLIβ“˜
0.31Tolerant
Observed/Expected LoF0.41 [0.20–0.94]
RankingsWhere PRAMEF27 stands among ~20K protein-coding genes
  • #19,212of 20,598
    Most Researched2
  • #8,750of 17,882
    Most Constrained (LOEUF)0.94
Genes detectedPRAMEF27
Sources retrieved0 papers
Response timeβ€”