RBM44 (RNA binding motif protein 44) is an RNA-binding protein that localizes to intercellular bridges (ICBs) connecting differentiating germ cells during meiosis 1. The protein contains an RNA recognition motif and is highly expressed in testis, with localization most prominent in pachytene and secondary spermatocytes 1. RBM44 interacts with TEX14, a critical ICB scaffolding protein, and participates in protein homodimerization 1. While RBM44 partially colocalizes with TEX14-positive ICBs, it is only limited to specific meiotic stages and disappears in spermatids 1. RBM44 may participate in RNA transport processes within ICBs and potentially in epigenetic regulation through interactions with small RNAs and other ICB protein complexes including KIAA1210 and MKLP1 2. Additionally, RBM44 localizes to the XY body of spermatocytes, suggesting roles beyond cell-cell communication 2. Notably, RBM44 is regulated post-transcriptionally by miR-34b-5p during meiosis 3. Despite its ICB localization, RBM44 deletion in mice does not impair male fertility, indicating it is nonessential for ICB stability maintenance or reproductive function 1, distinguishing it functionally from TEX14 and other critical ICB components.