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GeneE
1 sources retrieved Β· Most recent: April 2026 Β· Index updated 15 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
RBMY1F
RNA binding motif protein Y-linked family 1 member F
Chromosome Y Β· Yq11.223
NCBI Gene: 159163Ensembl: ENSG00000169800.14HGNC: HGNC:23917UniProt: J3KQ82
16PubMed Papers
1Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingidentical protein bindingmRNA splicing, via spliceosomemRNA bindingneoplasm
✦AI Summary

Based on limited published evidence, RBMY1F is an RNA-binding protein located on the Y chromosome Y in spermatogenesis. UniProt annotations indicate it participates in RNA binding and pre-mRNA splicing via the spliceosome in testis tissue, with roles in sperm development. GO terms support functions in mRNA binding, spliceosomal complex assembly, and protein binding. Clinical relevance is suggested by identification within a minimal critical region of AZFc deletions associated with testicular maturation arrest and male infertility 1.

Sources cited
1
RBMY1F identified within the minimal critical region (Y:24356128-24873665) of AZFc deletions associated with testicular maturation arrest and male infertility
PMID: 28217965
⚠Limited data available β€” This gene has 1 indexed publication. Summary and analysis may be incomplete.
Disease Associationsβ“˜1
neoplasmOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
FRG1Shared pathway100%MFAP1Shared pathway100%PLRG1Shared pathway100%RBM10Shared pathway100%BUD31Shared pathway100%CIRSRShared pathway100%
Tissue Expression6 tissues
Liver
0%
Brain
0%
Ovary
0%
Heart
0%
Lung
0%
Bone Marrow
0%
Gene Interaction Network
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RBMY1FFRG1MFAP1PLRG1RBM10BUD31CIRSR
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q15415
View on AlphaFold β†—
RankingsWhere RBMY1F stands among ~20K protein-coding genes
  • #15,364of 20,598
    Most Researched16
Genes detectedRBMY1F
Sources retrieved1 papers
Response timeβ€”
πŸ“„ Sources
1
1
Copy number variations in testicular maturation arrest.
PMID: 28217965
Andrology Β· 2017
1.00