RPP25L is a ribonuclease P/MRP subunit component involved in RNA processing. Based on limited published evidence, RPP25L shares functional redundancy with RPP25 and can physically and functionally compensate for RPP25 absence as a member of RNase P/MRP complexes in tRNA processing 1. The protein exhibits RNA binding capacity and participates in tRNA 5'-leader removal through the ribonuclease MRP complex.