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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
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SLC35D4
solute carrier family 35 member D4
Chromosome 18 Β· 18q11.2
NCBI Gene: 85019Ensembl: ENSG00000134490.14HGNC: HGNC:31723UniProt: B4DH40
16PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transporter
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
UDP-N-acetylglucosamine transmembrane transportprotein bindingUDP-N-acetylglucosamine transmembrane transporter activityGolgi apparatusosteoarthritisCOVID-19isolated asymptomatic elevation of creatine phosphokinasealopecia areata
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

solute carrier family 35 member D4

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
osteoarthritisOpen Targets
0.31Weak
COVID-19Open Targets
0.15Weak
isolated asymptomatic elevation of creatine phosphokinaseOpen Targets
0.06Suggestive
alopecia areataOpen Targets
0.06Suggestive
bronchiectasisOpen Targets
0.06Suggestive
primary ciliary dyskinesiaOpen Targets
0.06Suggestive
bronchiectasis with or without elevated sweat chloride 3Open Targets
0.05Suggestive
pentosuriaOpen Targets
0.04Suggestive
Young syndromeOpen Targets
0.04Suggestive
basal cell carcinomaOpen Targets
0.04Suggestive
primary ciliary dyskinesia 21Open Targets
0.04Suggestive
bronchiectasis with or without elevated sweat chloride 2Open Targets
0.04Suggestive
hypertensionOpen Targets
0.04Suggestive
Chronic mucocutaneous candidosisOpen Targets
0.04Suggestive
immunodeficiency 51Open Targets
0.04Suggestive
pseudohyperaldosteronism type 2Open Targets
0.04Suggestive
bronchiectasis with or without elevated sweat chloride 1Open Targets
0.04Suggestive
obesityOpen Targets
0.04Suggestive
Immunodeficiency by defective expression of HLA class 1Open Targets
0.04Suggestive
MHC class I deficiencyOpen Targets
0.04Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
SLC35B4Shared pathway100%SLC35D1Shared pathway50%SLC35D2Shared pathway50%SLC35A3Shared pathway25%
Tissue Expression6 tissues
Brain
100%
Liver
84%
Bone Marrow
83%
Lung
82%
Ovary
63%
Heart
52%
Gene Interaction Network
Click a node to explore
SLC35D4SLC35B4SLC35D1SLC35D2SLC35A3
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q24JQ0
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.17LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.88 [0.68–1.17]
RankingsWhere SLC35D4 stands among ~20K protein-coding genes
  • #15,386of 20,598
    Most Researched16
  • #12,278of 17,882
    Most Constrained (LOEUF)1.17
Genes detectedSLC35D4
Sources retrieved0 papers
Response timeβ€”