SLC35D4 — solute carrier family 35 member D4

5 sources retrieved · Most recent: April 2026 · Index updated 3 months ago

16PubMed Papers

#15,337 · top 79% of 19K genes

20Diseases

top 78%

0Drugs

0Pathogenic Variants

TransporterExperimental GO EvidenceSwiss-Prot Reviewed

UDP-N-acetylglucosamine transmembrane transportprotein bindingUDP-N-acetylglucosamine transmembrane transporter activityGolgi apparatusosteoarthritisCOVID-19isolated asymptomatic elevation of creatine phosphokinasealopecia areata

AI Summary

AI summary not yet available. Showing NCBI Gene summary.

solute carrier family 35 member D4

⚠Limited data available — This gene has 0 indexed publications. Summary and analysis may be incomplete.

Disease Associations20

osteoarthritisOpen Targets

0.31Weak

COVID-19Open Targets

0.15Weak

isolated asymptomatic elevation of creatine phosphokinaseOpen Targets

0.06Suggestive

alopecia areataOpen Targets

0.06Suggestive

bronchiectasisOpen Targets

0.06Suggestive

primary ciliary dyskinesiaOpen Targets

0.06Suggestive

bronchiectasis with or without elevated sweat chloride 3Open Targets

0.05Suggestive

pentosuriaOpen Targets

0.04Suggestive

Young syndromeOpen Targets

0.04Suggestive

basal cell carcinomaOpen Targets

0.04Suggestive

primary ciliary dyskinesia 21Open Targets

0.04Suggestive

bronchiectasis with or without elevated sweat chloride 2Open Targets

0.04Suggestive

hypertensionOpen Targets

0.04Suggestive

Chronic mucocutaneous candidosisOpen Targets

0.04Suggestive

immunodeficiency 51Open Targets

0.04Suggestive

pseudohyperaldosteronism type 2Open Targets

0.04Suggestive

bronchiectasis with or without elevated sweat chloride 1Open Targets

0.04Suggestive

obesityOpen Targets

0.04Suggestive

Immunodeficiency by defective expression of HLA class 1Open Targets

0.04Suggestive

MHC class I deficiencyOpen Targets

0.04Suggestive

Pathogenic Variants

No pathogenic variants reported on ClinVar for this gene.

Tissue Expression6 tissues

Brain

100%

Liver

84%

Bone Marrow

83%

Lung

82%

Ovary

63%

Heart

52%

Gene Interaction Network4 neighbors

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StructureAlphaFold

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AlphaFoldAI-predicted · UniProt Q24JQ0

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ConstraintgnomAD v4.1

LOEUFⓘ

1.17LoF Tolerant

pLIⓘ

0.00Tolerant

Observed/Expected LoF0.88 [0.68–1.17]

Rankings2 dim

Where SLC35D4 stands among ~20K protein-coding genes

#15,386of 20,598
Most Researched16
#12,278of 17,882
Most Constrained (LOEUF)1.17