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GeneE
0 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
SLC60A2
solute carrier family 60 member 2
Chromosome 6 Β· 6q21
NCBI Gene: 91749Ensembl: ENSG00000173214.7HGNC: HGNC:21053UniProt: B3KSA1
17PubMed Papers
20Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Transporter
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
protein bindingD-glucose:sodium symporter activityD-glucose import across plasma membranebrush border membranepsoriasissmoking initiationrisk-taking behaviourhemolytic anemia
✦AI Summary

AI summary not yet available. Showing NCBI Gene summary.

solute carrier family 60 member 2

⚠Limited data available β€” This gene has 0 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜20
psoriasisOpen Targets
0.37Weak
smoking initiationOpen Targets
0.12Weak
risk-taking behaviourOpen Targets
0.09Suggestive
hemolytic anemiaOpen Targets
0.05Suggestive
attention deficit hyperactivity disorderOpen Targets
0.03Suggestive
substance abuseOpen Targets
0.03Suggestive
cannabis dependenceOpen Targets
0.02Suggestive
smoking behaviorOpen Targets
0.02Suggestive
VertigoOpen Targets
0.02Suggestive
cancerOpen Targets
0.02Suggestive
breast cancerOpen Targets
0.01Suggestive
Pick diseaseOpen Targets
0.00Suggestive
colorectal cancerOpen Targets
0.00Suggestive
chronic kidney diseaseOpen Targets
0.00Suggestive
rheumatoid arthritisOpen Targets
0.00Suggestive
diabetes mellitusOpen Targets
0.00Suggestive
progressive supranuclear palsyOpen Targets
0.00Suggestive
chromophobe renal cell carcinomaOpen Targets
0.00Suggestive
metastatic melanomaOpen Targets
0.00Suggestive
dilated cardiomyopathyOpen Targets
0.00Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
SLC5A4Shared pathway67%PDZK1IP1Shared pathway50%SLC6A18Shared pathway33%ASIC4Shared pathway33%UNC79Shared pathway33%UNC80Shared pathway33%
Tissue Expression6 tissues
Liver
100%
Lung
70%
Ovary
64%
Brain
59%
Bone Marrow
56%
Heart
50%
Gene Interaction Network
Click a node to explore
SLC60A2SLC5A4PDZK1IP1SLC6A18ASIC4UNC79UNC80
PROTEIN STRUCTURE
Preparing viewer…
AlphaFoldAI-predicted Β· UniProt Q5TF39
View on AlphaFold β†—
Constraintβ“˜
LOEUFβ“˜
1.58LoF Tolerant
pLIβ“˜
0.00Tolerant
Observed/Expected LoF0.86 [0.49–1.58]
RankingsWhere SLC60A2 stands among ~20K protein-coding genes
  • #15,116of 20,598
    Most Researched17
  • #15,568of 17,882
    Most Constrained (LOEUF)1.58
Genes detectedSLC60A2
Sources retrieved0 papers
Response timeβ€”