2 sources retrieved · Most recent: April 2026 · Index updated 15 days ago
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8PubMed Papers
10Diseases
0Drugs
0Pathogenic Variants
DATA QUALITY✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
plasma membranepheromone bindingG protein-coupled receptor signaling pathwaymembraneneurodegenerative diseasealcohol drinkingtrauma complicationinfection
Based on limited published evidence, VN1R4 is a putative pheromone receptor localized to the plasma membrane with pheromone binding capability according to UniProt and GO annotations. However, no functional studies directly characterize VN1R4's role in pheromone detection. VN1R4 has been identified as a differentially expressed gene in radiation-induced thyroid carcinoma 1 and shows genomic aberrations in glioma samples 2, but these represent indirect associations in cancer-related gene expression profiling rather than direct functional characterization.
1
VN1R4 identified as commonly misregulated gene in high-dose radiation-induced thyroid carcinoma expression profiling
PMID: 270063822
VN1R4 shows genomic gains, losses, and copy-neutral loss of heterozygosity in glioma samples
PMID: 23451178⚠Limited data available — This gene has 2 indexed publications. Summary and analysis may be incomplete.
neurodegenerative diseaseOpen Targets
alcohol drinkingOpen Targets
trauma complicationOpen Targets
mental or behavioural disorderOpen Targets
Pneumocystis infectious diseaseOpen Targets
pneumocystosisOpen Targets
Langer mesomelic dysplasiaOpen Targets
hemochromatosisOpen Targets
No pathogenic variants reported on ClinVar for this gene.