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GeneE
2 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
β“˜GeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
OR7G3
olfactory receptor family 7 subfamily G member 3
Chromosome 19 Β· 19p13.2
NCBI Gene: 390883Ensembl: ENSG00000170920.2HGNC: HGNC:8467UniProt: A0A126GVR4
5PubMed Papers
3Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Receptor
DATA QUALITY
βœ“ Experimental GO Evidenceβœ“ Swiss-Prot Reviewed
olfactory receptor activityplasma membranesignal transductionsensory perception of chemical stimulushyperaldosteronismneuroblastomaalcohol drinking
✦AI Summary

Based on limited published evidence, OR7G3 is an olfactory receptor that functions as an odorant receptor localized to the plasma membrane and mediates signal transduction 1. A single nucleotide polymorphism (rs10414255) in OR7G3 was associated with adiposity and eating behaviors in a family-based study, suggesting potential involvement in appetite regulation 1. Additionally, OR7G3 methylation status was identified as a differentially methylated gene in bladder cancer tissues and integrated into a prognostic risk model for survival prediction 2, though the functional significance of this association remains unclear.

Sources cited
1
OR7G3 SNP (rs10414255) associated with adiposity and eating behaviors, suggesting olfactory receptors may influence appetite regulation
PMID: 22044667
2
OR7G3 identified as a differentially methylated gene in bladder cancer and incorporated into a prognostic survival risk model
PMID: 30953370
⚠Limited data available β€” This gene has 2 indexed publications. Summary and analysis may be incomplete.
Disease Associationsβ“˜3
hyperaldosteronismOpen Targets
0.03Suggestive
neuroblastomaOpen Targets
0.03Suggestive
alcohol drinkingOpen Targets
0.02Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar β†—
Related Genes
OR3A2Shared pathway100%OR1E2Shared pathway100%OR7C2Shared pathway100%OR1L3Shared pathway100%OR7G1Shared pathway100%OR1M1Shared pathway100%
Tissue Expression6 tissues
Lung
0%
Bone Marrow
0%
Ovary
0%
Heart
0%
Liver
0%
Brain
0%
Gene Interaction Network
Click a node to explore
OR7G3OR3A2OR1E2OR7C2OR1L3OR7G1OR1M1
PROTEIN STRUCTURE
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AlphaFoldAI-predicted Β· UniProt Q8NG95
View on AlphaFold β†—
RankingsWhere OR7G3 stands among ~20K protein-coding genes
  • #18,450of 20,598
    Most Researched5
Genes detectedOR7G3
Sources retrieved2 papers
Response timeβ€”
πŸ“„ Sources
2
1
Prognostic value of differentially methylated gene profiles in bladder cancer.
PMID: 30953370
J Cell Physiol Β· 2019
1.00
2
Association between olfactory receptor genes, eating behavior traits and adiposity: results from the Quebec Family Study.
PMID: 22044667
Physiol Behav Β· 2012
0.50