2 sources retrieved Β· Most recent: April 2026 Β· Index updated 14 days ago
βGeneE is for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment.
5PubMed Papers
3Diseases
0Drugs
0Pathogenic Variants
DATA QUALITYβ Experimental GO Evidenceβ Swiss-Prot Reviewed
olfactory receptor activityplasma membranesignal transductionsensory perception of chemical stimulushyperaldosteronismneuroblastomaalcohol drinking
Based on limited published evidence, OR7G3 is an olfactory receptor that functions as an odorant receptor localized to the plasma membrane and mediates signal transduction 1. A single nucleotide polymorphism (rs10414255) in OR7G3 was associated with adiposity and eating behaviors in a family-based study, suggesting potential involvement in appetite regulation 1. Additionally, OR7G3 methylation status was identified as a differentially methylated gene in bladder cancer tissues and integrated into a prognostic risk model for survival prediction 2, though the functional significance of this association remains unclear.
1
OR7G3 SNP (rs10414255) associated with adiposity and eating behaviors, suggesting olfactory receptors may influence appetite regulation
PMID: 220446672
OR7G3 identified as a differentially methylated gene in bladder cancer and incorporated into a prognostic survival risk model
PMID: 30953370β Limited data available β This gene has 2 indexed publications. Summary and analysis may be incomplete.
hyperaldosteronismOpen Targets
neuroblastomaOpen Targets
alcohol drinkingOpen Targets
No pathogenic variants reported on ClinVar for this gene.