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GeneE
1 sources retrieved · Most recent: April 2026 · Index updated 14 days ago
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OR7G1
olfactory receptor family 7 subfamily G member 1
Chromosome 19 · 19p13.2
NCBI Gene: 125962Ensembl: ENSG00000161807.3HGNC: HGNC:8465UniProt: A0A126GVS6
6PubMed Papers
3Diseases
0Drugs
0Pathogenic Variants
FUNCTIONAL ROLE
Receptor
DATA QUALITY
✓ Experimental GO Evidence✓ Swiss-Prot Reviewed
olfactory receptor activityplasma membranesignal transductionsensory perception of chemical stimulusneuroblastomahyperaldosteronismpancreatic adenocarcinoma
✦AI Summary

Based on limited published evidence, OR7G1 is an olfactory receptor that functions in odorant recognition and signal transduction at the plasma membrane. As a member of the olfactory receptor family 7 subfamily G, it mediates the detection of volatile organic compounds. Molecular docking studies indicate OR7G1 binds aroma-active compounds including δ-decalactone and 2-acetylpyrrole, suggesting a role in human aroma perception 1. However, functional characterization of this receptor remains largely unexplored.

Sources cited
1
OR7G1 demonstrates binding affinity for aroma-active compounds δ-decalactone and 2-acetylpyrrole through molecular docking, implicating it in aroma perception
PMID: 40428486
⚠Limited data available — This gene has 1 indexed publication. Summary and analysis may be incomplete.
Disease Associationsⓘ3
neuroblastomaOpen Targets
0.05Suggestive
hyperaldosteronismOpen Targets
0.05Suggestive
pancreatic adenocarcinomaOpen Targets
0.03Suggestive
Pathogenic Variants
No pathogenic variants reported on ClinVar for this gene.
View on ClinVar ↗
Related Genes
OR3A2Shared pathway100%OR1E2Shared pathway100%OR7C2Shared pathway100%OR1L3Shared pathway100%OR1D4Shared pathway100%OR7G3Shared pathway100%
Tissue Expression

No tissue expression data available for this gene.

Gene Interaction Network
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OR7G1OR3A2OR1E2OR7C2OR1L3OR1D4OR7G3
PROTEIN STRUCTURE
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AlphaFoldAI-predicted · UniProt Q8NGA0
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RankingsWhere OR7G1 stands among ~20K protein-coding genes
  • #18,172of 20,598
    Most Researched6
Genes detectedOR7G1
Sources retrieved1 papers
Response time—
📄 Sources
1
1
The New Aristocrat of Wuyi Rock Tea: Chemical Basis of the Unique Aroma Quality of "Laocong Shuixian".
PMID: 40428486
Foods · 2025
1.00